Validity of retrospective occupational exposure estimates of lead and manganese in a case–control study

• Published in: Occupational and environmental medicine (London, England) Vol. 76; no. 9; pp. 680 - 687
• Main Authors: Sauvé, Jean-François, Ramsay, Joemy M, Locke, Sarah J, Dopart, Pamela J, Josse, Pabitra R, Zaebst, Dennis D, Albert, Paul S, Cantor, Kenneth P, Baris, Dalsu, Jackson, Brian P, Karagas, Margaret R, Hosain, GM Monawar, Schwenn, Molly, Johnson, Alison, Purdue, Mark P, Koutros, Stella, Silverman, Debra T, Friesen, Melissa C
• Format: Journal Article
• Language: English
• Published: England BMJ Publishing Group Ltd 01.09.2019; BMJ; BMJ Publishing Group LTD
• Subjects: Adult; Aged; Assessments; Bioindicators; biological monitoring; Biological Monitoring - methods; Bladder; Bladder cancer; Case studies; Case-Control Studies; Control methods; Engines; Environmental studies; Epidemiology; Estimates; Evaluation; Experts; Exposure; Exposure assessment; Female; Hazardous materials; Heavy metals; Humans; Indicator species; Interviews; Laboratories; lead; Lead - analysis; Maine; Male; Manganese; Manganese - analysis; Metal concentrations; metals; Middle Aged; Nails - chemistry; New Hampshire; Occupational exposure; Occupational Exposure - analysis; Occupational health; Occupational safety; ORIGINAL ARTICLE; PCB; Polychlorinated biphenyls; Population; Population studies; Questionnaires; Ratings; Regression analysis; Regression models; retrospective exposure assessment; Retrospective Studies; Soldering; Studies; Toenail; Toxicology; Trends; Urine; Validity; Vermont; Vermont; Maine; New Hampshire; United States > US; United Kingdom > UK; England; biological monitoring; metals; retrospective exposure assessment; lead

ObjectivesThe validity of surrogate measures of retrospective occupational exposure in population-based epidemiological studies has rarely been evaluated. Using toenail samples as bioindicators of exposure, we assessed whether work tasks and expert assessments of occupational metal exposure obtained...