Hypokalemia: a clinical update

Hypokalemia is a common electrolyte disturbance, especially in hospitalized patients. It can have various causes, including endocrine ones. Sometimes, hypokalemia requires urgent medical attention. The aim of this review is to present updated information regarding: (1) the definition and prevalence...

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Published inEndocrine Connections Vol. 7; no. 4; pp. R135 - R146
Main Authors Kardalas, Efstratios, Paschou, Stavroula A, Anagnostis, Panagiotis, Muscogiuri, Giovanna, Siasos, Gerasimos, Vryonidou, Andromachi
Format Journal Article
LanguageEnglish
Published England Bioscientifica Ltd 01.04.2018
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Abstract Hypokalemia is a common electrolyte disturbance, especially in hospitalized patients. It can have various causes, including endocrine ones. Sometimes, hypokalemia requires urgent medical attention. The aim of this review is to present updated information regarding: (1) the definition and prevalence of hypokalemia, (2) the physiology of potassium homeostasis, (3) the various causes leading to hypokalemia, (4) the diagnostic steps for the assessment of hypokalemia and (5) the appropriate treatment of hypokalemia depending on the cause. Practical algorithms for the optimal diagnostic, treatment and follow-up strategy are presented, while an individualized approach is emphasized.
AbstractList Hypokalemia is a common electrolyte disturbance, especially in hospitalized patients. It can have various causes, including endocrine ones. Sometimes, hypokalemia requires urgent medical attention. The aim of this review is to present updated information regarding: (1) the definition and prevalence of hypokalemia, (2) the physiology of potassium homeostasis, (3) the various causes leading to hypokalemia, (4) the diagnostic steps for the assessment of hypokalemia and (5) the appropriate treatment of hypokalemia depending on the cause. Practical algorithms for the optimal diagnostic, treatment and follow-up strategy are presented, while an individualized approach is emphasized.
Hypokalemia is a common electrolyte disturbance, especially in hospitalized patients. It can have various causes, including endocrine ones. Sometimes, hypokalemia requires urgent medical attention. The aim of this review is to present updated information regarding: (1) the definition and prevalence of hypokalemia, (2) the physiology of potassium homeostasis, (3) the various causes leading to hypokalemia, (4) the diagnostic steps for the assessment of hypokalemia and (5) the appropriate treatment of hypokalemia depending on the cause. Practical algorithms for the optimal diagnostic, treatment and follow-up strategy are presented, while an individualized approach is emphasized.Hypokalemia is a common electrolyte disturbance, especially in hospitalized patients. It can have various causes, including endocrine ones. Sometimes, hypokalemia requires urgent medical attention. The aim of this review is to present updated information regarding: (1) the definition and prevalence of hypokalemia, (2) the physiology of potassium homeostasis, (3) the various causes leading to hypokalemia, (4) the diagnostic steps for the assessment of hypokalemia and (5) the appropriate treatment of hypokalemia depending on the cause. Practical algorithms for the optimal diagnostic, treatment and follow-up strategy are presented, while an individualized approach is emphasized.
Author Kardalas, Efstratios
Muscogiuri, Giovanna
Vryonidou, Andromachi
Paschou, Stavroula A
Siasos, Gerasimos
Anagnostis, Panagiotis
AuthorAffiliation Department of Endocrinology and Diabetes, Evangelismos Hospital, Athens, Greece
Division of Endocrinology, Department of Clinical Medicine and Surgery, ‘Federico II’ University of Naples, Naples, Italy
First Department of Cardiology, Hippokration Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece
Unit of Reproductive Endocrinology, First Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece
Department of Endocrinology and Diabetes, Hellenic Red Cross Hospital, Athens, Greece
Division of Endocrinology and Diabetes, ‘Aghia Sophia’ Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece
AuthorAffiliation_xml – name: Unit of Reproductive Endocrinology, First Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece
– name: Department of Endocrinology and Diabetes, Hellenic Red Cross Hospital, Athens, Greece
– name: Division of Endocrinology and Diabetes, ‘Aghia Sophia’ Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece
– name: Department of Endocrinology and Diabetes, Evangelismos Hospital, Athens, Greece
– name: Division of Endocrinology, Department of Clinical Medicine and Surgery, ‘Federico II’ University of Naples, Naples, Italy
– name: First Department of Cardiology, Hippokration Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece
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  givenname: Efstratios
  surname: Kardalas
  fullname: Kardalas, Efstratios
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  givenname: Stavroula A
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  fullname: Paschou, Stavroula A
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  surname: Anagnostis
  fullname: Anagnostis, Panagiotis
  organization: Unit of Reproductive Endocrinology, First Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece
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  givenname: Giovanna
  surname: Muscogiuri
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– sequence: 6
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  surname: Vryonidou
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  email: mahi_vr@hotmail.com
  organization: Department of Endocrinology and Diabetes, Hellenic Red Cross Hospital, Athens, Greece
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Issue 4
Keywords acid–base status
hypokalemia
potassium
kidneys
adrenal
electrolytes
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Snippet Hypokalemia is a common electrolyte disturbance, especially in hospitalized patients. It can have various causes, including endocrine ones. Sometimes,...
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SubjectTerms acid–base status
adrenal
Editor's Choice
electrolytes
hypokalemia
kidneys
potassium
Review
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Title Hypokalemia: a clinical update
URI http://dx.doi.org/10.1530/EC-18-0109
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