Networked buffering: a basic mechanism for distributed robustness in complex adaptive systems

• Published in: Theoretical biology and medical modelling Vol. 7; no. 1; p. 20
• Main Authors: Whitacre, James M, Bender, Axel
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 15.06.2010; BioMed Central
• Subjects: Analysis; Complex adaptive systems; Ecosystems; Genome; Models, Theoretical; Protein folding; Proteome; Stochastic processes
• ISSN: 1742-4682; 1742-4682
• DOI: 10.1186/1742-4682-7-20

A generic mechanism--networked buffering--is proposed for the generation of robust traits in complex systems. It requires two basic conditions to be satisfied: 1) agents are versatile enough to perform more than one single functional role within a system and 2) agents are degenerate, i.e. there exists partial overlap in the functional capabilities of agents. Given these prerequisites, degenerate systems can readily produce a distributed systemic response to local perturbations. Reciprocally, excess resources related to a single function can indirectly support multiple unrelated functions within a degenerate system. In models of genome:proteome mappings for which localized decision-making and modularity of genetic functions are assumed, we verify that such distributed compensatory effects cause enhanced robustness of system traits. The conditions needed for networked buffering to occur are neither demanding nor rare, supporting the conjecture that degeneracy may fundamentally underpin distributed robustness within several biotic and abiotic systems. For instance, networked buffering offers new insights into systems engineering and planning activities that occur under high uncertainty. It may also help explain recent developments in understanding the origins of resilience within complex ecosystems.