Application of the Human Intestinal Tract Chip to the non-human primate gut microbiota

The human intestinal microbiota is responsible for various health-related functions, and its diversity can be readily mapped with the 16S ribosomal RNA targeting Human Intestinal Tract (HIT) Chip. Here we characterise distal gut samples from chimpanzees, gorillas and marmosets, and compare them with...

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Bibliographic Details
Published inBeneficial microbes Vol. 6; no. 3; p. 271
Main Authors Bello González, T D J, van Passel, M W J, Tims, S, Fuentes, S, De Vos, W M, Smidt, H, Belzer, C
Format Journal Article
LanguageEnglish
Published Netherlands 2015
Subjects
Animals
Bacteria - classification
Bacteria - genetics
Bacteria - isolation & purification
DNA, Bacterial - genetics
Feces - microbiology
Gastrointestinal Microbiome
Gorilla gorilla - microbiology
Humans
Intestines - microbiology
Oligonucleotide Array Sequence Analysis
Pan troglodytes - microbiology
Phylogeny
RNA, Ribosomal, 16S - genetics
microbiota
non-human primates
phylogenetic profile
enterotypes
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Summary:The human intestinal microbiota is responsible for various health-related functions, and its diversity can be readily mapped with the 16S ribosomal RNA targeting Human Intestinal Tract (HIT) Chip. Here we characterise distal gut samples from chimpanzees, gorillas and marmosets, and compare them with human gut samples. Our results indicated applicability of the HITChip platform can be extended to chimpanzee and gorilla faecal samples for analysis of microbiota composition and enterotypes, but not to the evolutionary more distant marmosets.
ISSN:1876-2891
DOI:10.3920/BM2014.0087