Dermoscopy for melanoma detection and triage in primary care: a systematic review

• Published in: BMJ open Vol. 9; no. 8; p. e027529
• Main Authors: Jones, OT, Jurascheck, LC, van Melle, MA, Hickman, S, Burrows, NP, Hall, PN, Emery, J, Walter, FM
• Format: Journal Article
• Language: English
• Published: England BMJ Publishing Group LTD 01.08.2019; BMJ Publishing Group
• Subjects: Accuracy; Bias; Biopsy; Cost analysis; Dermatology; Dermoscopy - methods; General practice / Family practice; Humans; Medical referrals; Melanoma; Melanoma - diagnosis; Microscopy; Patient satisfaction; Patients; Physicians; Primary care; Primary Health Care; Reproducibility of Results; Skin cancer; Skin Neoplasms - diagnosis; Systematic review; Triage - methods; United Kingdom > UK; skin cancer; melanoma; primary care; systematic review; dermoscopy
• ISSN: 2044-6055; 2044-6055
• DOI: 10.1136/bmjopen-2018-027529

ObjectiveMost skin lesions first present in primary care, where distinguishing rare melanomas from benign lesions can be challenging. Dermoscopy improves diagnostic accuracy among specialists and is promoted for use by primary care physicians (PCPs). However, when used by untrained clinicians, accuracy may be no better than visual inspection. This study aimed to undertake a systematic review of literature reporting use of dermoscopy to triage suspicious skin lesions in primary care settings, and challenges for implementation.DesignA systematic literature review and narrative synthesis.Data sourcesWe searched MEDLINE, Cochrane Central, EMBASE, Cumulative Index to Nursing and Allied Health Literature, and SCOPUS bibliographic databases from 1 January 1990 to 31 December 2017, without language restrictions.Inclusion criteriaStudies including assessment of dermoscopy accuracy, acceptability to patients and PCPs, training requirements, and cost-effectiveness of dermoscopy modes in primary care, including trials, diagnostic accuracy and acceptability studies.Results23 studies met the review criteria, representing 49 769 lesions and 3708 PCPs, all from high-income countries. There was a paucity of studies set truly in primary care and the outcomes measured were diverse. The heterogeneity therefore made meta-analysis unfeasible; the data were synthesised through narrative review. Dermoscopy, with appropriate training, was associated with improved diagnostic accuracy for melanoma and benign lesions, and reduced unnecessary excisions and referrals. Teledermoscopy-based referral systems improved triage accuracy. Only three studies examined cost-effectiveness; hence, there was insufficient evidence to draw conclusions. Costs, training and time requirements were considered important implementation barriers. Patient satisfaction was seldom assessed. Computer-aided dermoscopy and other technological advances have not yet been tested in primary care.ConclusionsDermoscopy could help PCPs triage suspicious lesions for biopsy, urgent referral or reassurance. However, it will be important to establish further evidence on minimum training requirements to reach competence, as well as the cost-effectiveness and patient acceptability of implementing dermoscopy in primary care.Trial registration numberCRD42018091395.