Transient psychosis due to painless thyroiditis in a patient with anxiety disorder: a case report

There are few reports on thyrotoxic psychosis caused by diseases other than Graves' disease or toxic nodular goiter. A 64-year-old Japanese woman was treated for anxiety disorder in our clinic for 10 years. She had five episodes of transient psychosis during the first five years. When she devel...

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Bibliographic Details
Published inJournal of medical case reports Vol. 5; no. 1; p. 534
Main Authors Kobayashi, Nobuyuki, Tajiri, Junichi, Takano, Masahiro
Format Journal Article
LanguageEnglish
Published England BioMed Central Ltd 31.10.2011
BioMed Central
BMC
Subjects
Anxiety
Care and treatment
Case Report
Case studies
Complications and side effects
Diagnosis
Psychoses
Risk factors
Thyroid diseases
Japan
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Summary:There are few reports on thyrotoxic psychosis caused by diseases other than Graves' disease or toxic nodular goiter. A 64-year-old Japanese woman was treated for anxiety disorder in our clinic for 10 years. She had five episodes of transient psychosis during the first five years. When she developed psychosis without neck pain 10 years after her first visit, a laboratory reexamination revealed that she had subclinical hyperthyroidism, and tested positive for antithyroid autoantibodies, negative for thyroid stimulating hormone receptor antibody and had decreased radioactive iodine uptake. She was diagnosed as having painless thyroiditis. The hyperthyroidism disappeared within a month, and the psychosis lasted for three months. To the best of our knowledge, this is the first report of psychosis due to painless thyroiditis-induced hyperthyroidism. Physical symptoms of painless thyroiditis are often so mild that careful differential diagnosis is necessary in the cases of transient psychosis.
ISSN:1752-1947
1752-1947
DOI:10.1186/1752-1947-5-534