Relation between C reactive protein and depression remission status in patients presenting with acute coronary syndrome

• Published in: Heart (British Cardiac Society) Vol. 92; no. 9; pp. 1316 - 1318
• Main Authors: Shimbo, D, Rieckmann, N, Paulino, R, Davidson, K W
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group Ltd and British Cardiovascular Society 01.09.2006; BMJ; BMJ Publishing Group LTD; BMJ Group
• Subjects: ACS; acute coronary syndrome; Acute coronary syndromes; Angina, Unstable - metabolism; Angina, Unstable - psychology; BDI; Beck Depression Inventory; Biological and medical sciences; Body mass index; C reactive protein; C-Reactive Protein - metabolism; Cardiology. Vascular system; Cohort Studies; COPES; Coronary heart disease; Coronary Psychosocial Patient Evaluation Study; CRP; Depressive Disorder - etiology; Depressive Disorder - metabolism; Female; Heart; Heart attacks; Humans; Male; Medical sciences; Middle Aged; Myocardial Infarction - metabolism; Myocardial Infarction - psychology; Recurrence; Scientific Letter; Studies; Syndrome; Mood disorder; Human; Acute; Cardiovascular disease; Depression; Remission; Circulatory system; Cardiology; C reactive protein; Coronary heart disease; Phlebology
• ISSN: 1355-6037; 1468-201X; 1468-201X
• DOI: 10.1136/hrt.2005.075861

[...]the final study sample comprised 100 patients. Spontaneous improvement in BDI scores after an ACS hospitalisation is associated with a significantly greater survival of patients with at least mild baseline depressive symptoms than of patients whose BDI scores remain raised. 5 Our data suggest a dose-response-like relation between depression remission status after an ACS event and raised CRP concentrations. [...]the lower survival rate observed among persistently depressed patients may be associated with raised CRP concentrations and, conversely, the higher survival rate observed among patients with remittent depression may be associated with lower CRP concentrations.