Co-existing sarcoidosis and Takayasu arteritis: report of a case

• Published in: International archives of medicine Vol. 4; no. 1; p. 9
• Main Authors: Hamzaoui, Amira, Salem, Randa, Klii, Rim, Harzallah, Olfa, Berriche, Olfa, Golli, Mondher, Mahjoub, Silvia
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 23.02.2011; BioMed Central
• Subjects: Arteritis; Care and treatment; Case Report; Case studies; Complications and side effects; Diagnosis; Risk factors; Sarcoidosis; Tunisia
• ISSN: 1755-7682; 1755-7682
• DOI: 10.1186/1755-7682-4-9

Takayasu arteritis (TA) is a chronic vasculitis of unknown origin, affecting mainly the aorta and its main branches. As a result of the inflammation, stenosis, occlusion or dilatation of the involved vessels may occur and cause a wide range of symptoms. It has been described in association with various auto-immune disorders (mainly inflammatory digestive tract diseases). However, only few cases of TA associated with sarcoidosis have been reported, raising the question of an association by chance. We report a case of a 34 year-old woman, with one year history of sarcoidosis, who presented with asymmetric high hypertension revealing inflammatory humeral, axillary and subclavian arteritis related to TA, successfully treated by steroid and immunosuppressive therapy(MethotrexateR). TA and sarcoidosis may be related, rising the hypothesis that TA or Takayasu arteritis-like granulomatous vasculitis may be, in fact, a complication of sarcoidosis.