Analysis of deaths while waiting for cardiac surgery among 29 293 consecutive patients in Ontario, Canada

Objectives To assess death rates among patients waiting for cardiac valve surgery or isolated coronary artery bypass surgery (CABG), and to determine independent risk factors for death while waiting for isolated CABG. Design Prospective cohort analysis based on an inclusive registry. Setting Nine ca...

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Published inHeart (British Cardiac Society) Vol. 79; no. 4; pp. 345 - 349
Main Authors Morgan, C D, Sykora, K, Naylor, C D
Format Journal Article
LanguageEnglish
Published London BMJ Publishing Group Ltd and British Cardiovascular Society 01.04.1998
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Abstract Objectives To assess death rates among patients waiting for cardiac valve surgery or isolated coronary artery bypass surgery (CABG), and to determine independent risk factors for death while waiting for isolated CABG. Design Prospective cohort analysis based on an inclusive registry. Setting Nine cardiac surgical units in Ontario, Canada. Patients 29 293 consecutive patients scheduled for cardiac surgery between October 1991 and June 1995. Main outcome measures Death rates while waiting for surgery were determined among patients scheduled for isolated CABG, isolated valve surgery, or combined procedures. Predictors of death among patients with isolated CABG were determined from multivariate analysis. Results There were 141 deaths (0.48%) among 29 293 patients. Adjusting for age, sex, and waiting time, patients waiting for valve surgery had a significantly increased risk of death compared with patients waiting for CABG alone (adjusted odds ratio 1.88, 95% confidence interval (CI) 1.23 to 2.88, p = 0.004). Results were similar for patients waiting for combined valve and CABG procedures compared with those who were waiting for isolated CABG. Independent risk factors for death while waiting for isolated CABG included: impaired left ventricular function (odds ratio 2.47, 95% CI 1.59 to 3.84, p < 0.001); advancing age (for each decade, odds ratio 1.41, 95% CI 1.10 to 1.80, p = 0.007); male sex (odds ratio 1.95, 95% CI 1.00 to 3.81, p = 0.05); and waiting longer than the maximum time recommended in Canadian guidelines for a patient’s clinical profile (odds ratio 1.59, 95% CI 1.01 to 2.51, p = 0.044). After scaling waiting time to surgery or death continuously in days, the same predictors emerged. Conclusions Patients waiting for valve surgery have a higher risk of death than patients waiting for isolated CABG. Guidelines to promote safer and fairer queuing for non-CABG cardiac surgery are needed. Shorter waiting lists, better compliance with existing guidelines, and guideline revisions to upgrade patients with left ventricular dysfunction could generate additional reductions in the already low risk of death for patients waiting for isolated CABG.
AbstractList Objectives —To assess death rates among patients waiting for cardiac valve surgery or isolated coronary artery bypass surgery (CABG), and to determine independent risk factors for death while waiting for isolated CABG.
 Design —Prospective cohort analysis based on an inclusive registry.
 Setting —Nine cardiac surgical units in Ontario, Canada.
 Patients —29 293 consecutive patients scheduled for cardiac surgery between October 1991 and June 1995.
 Main outcome measures —Death rates while waiting for surgery were determined among patients scheduled for isolated CABG, isolated valve surgery, or combined procedures. Predictors of death among patients with isolated CABG were determined from multivariate analysis.
 Results —There were 141 deaths (0.48%) among 29 293 patients. Adjusting for age, sex, and waiting time, patients waiting for valve surgery had a significantly increased risk of death compared with patients waiting for CABG alone (adjusted odds ratio 1.88, 95% confidence interval (CI) 1.23 to 2.88, p = 0.004). Results were similar for patients waiting for combined valve and CABG procedures compared with those who were waiting for isolated CABG. Independent risk factors for death while waiting for isolated CABG included: impaired left ventricular function (odds ratio 2.47, 95% CI 1.59   to 3.84, p < 0.001); advancing age (for each decade, odds ratio 1.41, 95% CI 1.10 to 1.80, p = 0.007); male sex (odds ratio 1.95,   95% CI 1.00 to 3.81, p = 0.05); and waiting longer than the maximum time recommended in Canadian guidelines for a patient's clinical profile (odds ratio 1.59, 95% CI 1.01 to 2.51, p = 0.044). After scaling waiting time to surgery or death continuously in days, the same predictors emerged.
 Conclusions —Patients waiting for valve surgery have a higher risk of death than patients waiting for isolated CABG. Guidelines to promote safer and fairer queuing for non-CABG cardiac surgery are needed. Shorter waiting lists, better compliance with existing guidelines, and guideline revisions to upgrade patients with left ventricular dysfunction could generate additional reductions in the already low risk of death for patients waiting for isolated CABG.

 Keywords: cardiac surgery;  waiting lists;  rationing
Objectives To assess death rates among patients waiting for cardiac valve surgery or isolated coronary artery bypass surgery (CABG), and to determine independent risk factors for death while waiting for isolated CABG. Design Prospective cohort analysis based on an inclusive registry. Setting Nine cardiac surgical units in Ontario, Canada. Patients 29 293 consecutive patients scheduled for cardiac surgery between October 1991 and June 1995. Main outcome measures Death rates while waiting for surgery were determined among patients scheduled for isolated CABG, isolated valve surgery, or combined procedures. Predictors of death among patients with isolated CABG were determined from multivariate analysis. Results There were 141 deaths (0.48%) among 29 293 patients. Adjusting for age, sex, and waiting time, patients waiting for valve surgery had a significantly increased risk of death compared with patients waiting for CABG alone (adjusted odds ratio 1.88, 95% confidence interval (CI) 1.23 to 2.88, p = 0.004). Results were similar for patients waiting for combined valve and CABG procedures compared with those who were waiting for isolated CABG. Independent risk factors for death while waiting for isolated CABG included: impaired left ventricular function (odds ratio 2.47, 95% CI 1.59 to 3.84, p < 0.001); advancing age (for each decade, odds ratio 1.41, 95% CI 1.10 to 1.80, p = 0.007); male sex (odds ratio 1.95, 95% CI 1.00 to 3.81, p = 0.05); and waiting longer than the maximum time recommended in Canadian guidelines for a patient’s clinical profile (odds ratio 1.59, 95% CI 1.01 to 2.51, p = 0.044). After scaling waiting time to surgery or death continuously in days, the same predictors emerged. Conclusions Patients waiting for valve surgery have a higher risk of death than patients waiting for isolated CABG. Guidelines to promote safer and fairer queuing for non-CABG cardiac surgery are needed. Shorter waiting lists, better compliance with existing guidelines, and guideline revisions to upgrade patients with left ventricular dysfunction could generate additional reductions in the already low risk of death for patients waiting for isolated CABG.
Objectives To assess death rates among patients waiting for cardiac valve surgery or isolated coronary artery bypass surgery (CABG), and to determine independent risk factors for death while waiting for isolated CABG. Design Prospective cohort analysis based on an inclusive registry. Setting Nine cardiac surgical units in Ontario, Canada. Patients 29â[euro][per thousand]293 consecutive patients scheduled for cardiac surgery between October 1991 and June 1995. Main outcome measures Death rates while waiting for surgery were determined among patients scheduled for isolated CABG, isolated valve surgery, or combined procedures. Predictors of death among patients with isolated CABG were determined from multivariate analysis. Results There were 141 deaths (0.48%) among 29â[euro][per thousand]293 patients. Adjusting for age, sex, and waiting time, patients waiting for valve surgery had a significantly increased risk of death compared with patients waiting for CABG alone (adjusted odds ratio 1.88, 95% confidence interval (CI) 1.23 to 2.88, pâ[euro][per thousand]=â[euro][per thousand]0.004). Results were similar for patients waiting for combined valve and CABG procedures compared with those who were waiting for isolated CABG. Independent risk factors for death while waiting for isolated CABG included: impaired left ventricular function (odds ratio 2.47, 95% CI 1.59 to 3.84, pâ[euro][per thousand]<â[euro][per thousand]0.001); advancing age (for each decade, odds ratio 1.41, 95% CI 1.10 to 1.80, pâ[euro][per thousand]=â[euro][per thousand]0.007); male sex (odds ratio 1.95, 95% CI 1.00 to 3.81, pâ[euro][per thousand]=â[euro][per thousand]0.05); and waiting longer than the maximum time recommended in Canadian guidelines for a patient's clinical profile (odds ratio 1.59, 95% CI 1.01 to 2.51, pâ[euro][per thousand]=â[euro][per thousand]0.044). After scaling waiting time to surgery or death continuously in days, the same predictors emerged. Conclusions Patients waiting for valve surgery have a higher risk of death than patients waiting for isolated CABG. Guidelines to promote safer and fairer queuing for non-CABG cardiac surgery are needed. Shorter waiting lists, better compliance with existing guidelines, and guideline revisions to upgrade patients with left ventricular dysfunction could generate additional reductions in the already low risk of death for patients waiting for isolated CABG.
Author Sykora, K
Morgan, C D
Naylor, C D
AuthorAffiliation Department of Medicine, Sunnybrook Health Science Centre, University of Toronto, Ontario, Canada
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Keywords Human
Prognosis
Treatment
Aortocoronary
Bypass
Follow up study
Surgery
Mortality
Heart valve
Waiting time
Language English
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Dr C D Morgan, E203, Sunnybrook Health Science Centre, 2075 Bayview Avenue, North York, Ontario, Canada M4N 3M5. Reprint requests to: Dr C D Naylor, G106, Sunnybrook Health Science Centre, 2075 Bayview Avenue, North York, Ontario, Canada M4N 3M5.
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Bernstein, Rigter, Brorsson 1997; 42
Naylor 1991; 10
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Naylor, Levinton, Baigrie 1992; 7
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Bengtson, Karlsson, Hjalmarson 1997; 17
Maggioni, Maseri, Fresco 1993; 329
Naylor, Slaughter 1994; 3
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Snippet Objectives To assess death rates among patients waiting for cardiac valve surgery or isolated coronary artery bypass surgery (CABG), and to determine...
Objectives —To assess death rates among patients waiting for cardiac valve surgery or isolated coronary artery bypass surgery (CABG), and to determine...
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StartPage 345
SubjectTerms Angina pectoris
Biological and medical sciences
cardiac surgery
Cardiovascular disease
Coronary vessels
Diabetes
Heart surgery
Medical sciences
Mortality
Patients
rationing
Regression analysis
Risk factors
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the heart
Variables
Vein & artery diseases
waiting lists
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Title Analysis of deaths while waiting for cardiac surgery among 29 293 consecutive patients in Ontario, Canada
URI http://dx.doi.org/10.1136/hrt.79.4.345
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https://pubmed.ncbi.nlm.nih.gov/PMC1728656
Volume 79
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