The SET-domain protein superfamily: protein lysine methyltransferases

The SET-domain protein methyltransferase superfamily includes all but one of the proteins known to methylate histones on lysine. Histone methylation is important in the regulation of chromatin and gene expression.

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Bibliographic Details
Published inGenome biology Vol. 6; no. 8; p. 227
Main Authors Dillon, Shane C, Zhang, Xing, Trievel, Raymond C, Cheng, Xiaodong
Format Journal Article
LanguageEnglish
Published England BioMed Central Ltd 2005
BioMed Central
Subjects
Animals
chromatin
Evolution, Molecular
gene expression
Histone-Lysine N-Methyltransferase - chemistry
Histone-Lysine N-Methyltransferase - classification
Histone-Lysine N-Methyltransferase - genetics
Histone-Lysine N-Methyltransferase - metabolism
histones
Humans
lysine
Methylation
methyltransferases
Models, Molecular
Multigene Family
Protein Structure, Tertiary
Review
Online AccessGet full text
ISSN1465-6906
1474-760X
1474-760X
1465-6914
DOI10.1186/gb-2005-6-8-227

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Summary:The SET-domain protein methyltransferase superfamily includes all but one of the proteins known to methylate histones on lysine. Histone methylation is important in the regulation of chromatin and gene expression.
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ISSN:1465-6906
1474-760X
1474-760X
1465-6914
DOI:10.1186/gb-2005-6-8-227