“Rheumatoid nodules” and lymphoma

• Published in: Annals of the rheumatic diseases Vol. 57; no. 10; pp. 578 - 579
• Main Authors: Courtney, P A, Wright, G D, Finch, M B
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group Ltd and European League Against Rheumatism 01.10.1998; BMJ; BMJ Publishing Group LTD
• Subjects: Abdomen; Biological and medical sciences; Biopsy; Female; Follow-Up Studies; Hematologic and hematopoietic diseases; Humans; Lesson of the Month; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis; Lymphocytes; Lymphoma; Lymphoma, B-Cell - complications; Medical sciences; Middle Aged; Paraneoplastic Syndromes - etiology; Paraneoplastic Syndromes - pathology; Rheumatoid arthritis; Rheumatoid Nodule - etiology; Rheumatoid Nodule - pathology; Human; Immunopathology; Skin disease; Diseases of the osteoarticular system; Panniculitis; Autoimmune disease; Malignant hemopathy; Inflammatory joint disease; B-Lymphocyte; Non Hodgkin lymphoma; Lymphoma; Hand; Differential diagnostic; Nodule; Case study; Symptomatology; Chronic; Lymphoproliferative syndrome; Rheumatoid arthritis; Upper limb; Paraneoplastic syndrome; Adipose tissue disorders; Elderly; Inaugural sign
• ISSN: 0003-4967; 1468-2060
• DOI: 10.1136/ard.57.10.578

Full blood count and differential, erythrocyte sedimentation rate (ESR), C reactive protein (CRP), rheumatoid factor, nuclear antibody profile, thyroid function. Seronegative polyarthritis has been reported as a rheumatological manifestation of B and T cell lymphomas 2 5 6 and arthritis indistinguishable from seronegative rheumatoid arthritis has been described in association with cutaneous T cell lymphoma. 2 The RS3PE syndrome (remitting seronegative symmetrical synovitis with pitting oedema) 7 has been reported in association with non-Hodgkin's lymphoma 8 and other malignant tumours. 9 Although there are features to support this diagnosis in this patient-that is, symmetrical seronegative synovitis with pitting oedema, remitting with a modest dose of corticosteroid; the normal inflammatory indices, nodulosis and panniculitis are not typical.