Changes in cerebral blood flow during anaesthesia and surgery in the sitting position

• Published in: Journal of neurology, neurosurgery and psychiatry Vol. 50; no. 8; pp. 971 - 975
• Main Authors: Nelson, R J, Lovick, A H, Pickard, J D, Brice, J, Saunders, D, Horsey, P J
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group Ltd 01.08.1987; BMJ; BMJ Publishing Group LTD
• Subjects: Adult; Aged; Anesthesia; Anesthesia depending on type of surgery; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Biological and medical sciences; Blood Pressure - drug effects; Brain - surgery; Cerebrovascular Circulation - drug effects; Female; Heart Rate - drug effects; Humans; Male; Medical sciences; Middle Aged; Neurosurgery; Postoperative Complications; Posture; Supination; Human; Surgery; Seated position; General anesthesia; Brain (Vertebrata); Nervous system; Hemodynamics; Blood flow
• ISSN: 0022-3050; 1468-330X
• DOI: 10.1136/jnnp.50.8.971

Serial measurements of global cerebral blood flow (CBF) were made in 15 patients undergoing elective neurosurgical procedures in the sitting position, using a modified intravenous 133Xenon technique. The mean supine CBF rose from 43 (+/-3) ml/100g/min to 62 (+/-6) ml/100g/min in the sitting position and remained elevated at the end of surgery at 62 (+/-5) ml/100g/min. Both increases in CBF were statistically significant with respect to baseline supine values.