An Update on Potential Molecular Mechanisms Underlying the Actions of Snake Venom L-amino Acid Oxidases (LAAOs)

• Published in: Current medicinal chemistry Vol. 25; no. 21; p. 2520
• Main Authors: Paloschi, Mauro V, Pontes, Adriana S, Soares, Andreimar M, Zuliani, Juliana P
• Format: Journal Article
• Language: English
• Published: United Arab Emirates 01.01.2018
• Subjects: LAAO; Snake venom; inflammation; mechanism of action; apoptosis; microbicidal; aggregation; biomedical potential

LAAOs (EC 1.4.3.2) are found in concentrations that vary according to each species of snakes; Viperidae, Crotalidae and Elapidae contain 1-9% of this enzyme in their venoms. This review focuses on an update on molecular mechanisms, platelet activities, antimicrobial, antiprotozoal, induction of apop...