Lung Transplantation in a Patient with Fibrosing Alveolitis
The transplantation of the right lung into a man aged 40 who was suffering from cryptogenic fibrosing alveolitis is described. Before transplantation he had been dependent on oxygen, even at rest, for 24 hours a day for almost two years. The donor was a boy of 16 years who had had a fatal cerebral h...
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Published in | British Medical Journal Vol. 3; no. 5771; pp. 391 - 398 |
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Main Authors | , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
England
British Medical Journal Publishing Group
14.08.1971
British Medical Association BMJ Publishing Group LTD |
Subjects | |
Online Access | Get full text |
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Summary: | The transplantation of the right lung into a man aged 40 who was suffering from cryptogenic fibrosing alveolitis is described. Before transplantation he had been dependent on oxygen, even at rest, for 24 hours a day for almost two years. The donor was a boy of 16 years who had had a fatal cerebral haemorrhage. The transplanted lung functioned perfectly from the time of operation until the patient's sudden death two months later from an overwhelming haemoptysis apparently from a small peribronchial abscess rupturing into the pulmonary artery. By the third postoperative week the patient had been able to walk unaided and without distress outdoors. The problem of differentiating infection from incipient rejection is discussed. We conclude that clinically successful lung transplantation can be achieved, but only if the problems of lung function, infection, and immunosuppression can all be overcome. |
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Bibliography: | istex:1E96367626C6B52F61F9DEEC1DC8DEFF70BC3EFD ark:/67375/NVC-GCFWQCM8-L href:bmj-3-391.pdf local:bmj;3/5771/391 PMID:4105315 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0007-1447 1468-5833 |
DOI: | 10.1136/bmj.3.5771.391 |