Cyclophosphamide-induced syndrome of inappropriate antidiuretic hormone secretion

Syndrome of inappropriate antidiuretic hormone (SIADH) is characterized by hyponatremia because of dilution of body fluids by an excess of water relative to total solute. Inappropriate secretion of the antidiuretic hormone (ADH), also known as vasopressin, due to any cause interferes with renal excr...

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Published inIndian journal of dermatology, venereology, and leprology Vol. 75; no. 6; p. 629
Main Authors Natarajan, Karthika, Srinivas, C. R, Jayachandran, K, Ramanathan, R. M. P. L
Format Journal Article
LanguageEnglish
Published India Medknow Publications on behalf of The Indian Association of Dermatologists, Venereologists and Leprologists (IADVL) 01.11.2009
Medknow Publications and Media Pvt. Ltd
Scientific Scholar
Subjects
Adult
Body fluids
Complications and side effects
Cyclophosphamide
Cyclophosphamide - adverse effects
Drugs
Female
Heart failure
Humans
Hyponatremia
Immunosuppressive Agents - adverse effects
Kidneys
Patient care planning
Pemphigus - drug therapy
Physical examinations
Physiological aspects
Pituitary ACTH Hypersecretion - chemically induced
Risk factors
Thyroid diseases
Vasopressin
India
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Summary:Syndrome of inappropriate antidiuretic hormone (SIADH) is characterized by hyponatremia because of dilution of body fluids by an excess of water relative to total solute. Inappropriate secretion of the antidiuretic hormone (ADH), also known as vasopressin, due to any cause interferes with renal excretion of water and results in production of concentrated urine and hyponatremia.
ISSN:0378-6323
0973-3922
1998-3611
DOI:10.4103/0378-6323.57739