Paget's disease of the breast in a man without underlying breast carcinoma

• Published in: Journal of clinical pathology Vol. 47; no. 9; pp. 851 - 852
• Main Authors: O'Sullivan, S T, McGreal, G T, Lyons, A, Burke, L, Geoghegan, J G, Brady, M P
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group Ltd and Association of Clinical Pathologists 01.09.1994; BMJ; BMJ Publishing Group LTD
• Subjects: Aged; Biological and medical sciences; Breast Neoplasms, Male - pathology; Dermatology; Epidermis - pathology; Gynecology. Andrology. Obstetrics; Humans; Male; Mammary gland diseases; Medical sciences; Nipples - pathology; Paget's Disease, Mammary - pathology; Tumors; Tumors of the skin and soft tissue. Premalignant lesions; Case study; Human; Mammary gland diseases; Skin disease; Paget disease; Sex; Male
• ISSN: 0021-9746; 1472-4146
• DOI: 10.1136/jcp.47.9.851

A case of histologically confirmed Paget's disease of the breast in a 72 year old man, without underlying breast carcinoma, is reported. This report raises questions about the pathogenesis of this condition and suggests that Paget's disease is an independent, intraepidermal carcinoma rather than a direct extension of intraductal carcinoma of the breast to the nipple and areola.