Ki-67 is expressed in multiplying forms of Schistosoma mansoni   , but not in snail host tissues

• Published in: Memórias do Instituto Oswaldo Cruz Vol. 102; no. 5; pp. 651 - 653
• Main Authors: Silva, Tânia Maria Correia, dos Santos Souza, Samaly, de Almeida, Tais Fontoura, Andrade, Zilton A
• Format: Journal Article
• Language: English
• Published: Brazil Fundação Oswaldo Cruz, Fiocruz 01.08.2007; Instituto Oswaldo Cruz, Ministério da Saúde; Fundação Oswaldo Cruz (FIOCRUZ)
• Subjects: Animals; Biomphalaria - cytology; Biomphalaria - parasitology; Biomphalaria glabrata; Hemocytes - chemistry; Host-Parasite Interactions - physiology; Immunohistochemistry; Ki-67; Ki-67 Antigen - metabolism; Mice; Mitotic Index; PARASITOLOGY; Schistosoma mansoni; Schistosoma mansoni - physiology; Staining and Labeling; TROPICAL MEDICINE; Ki-67; Schistosoma mansoni; Biomphalaria glabrata
• ISSN: 1678-8060; 0074-0276; 1678-8060
• DOI: 10.1590/S0074-02762007005000063

Ki-67 is a protein expressed in the nucleus of several species during cell-division, being absent during the GO resting phase of the cellular cycle. During attempts to disclose mitosis in the so-called "amebocyte-producing organ" in Biomphalaria glabrata   infected with Schistosoma mansoni, the parasite multiplying forms appeared strongly marked for Ki-67, while the snail tissues were completely negative. These data are worth registering to complement general data on Ki-67, and to help future studies on the relationship of the parasite and of its intermediate host.