Coffee consumption and the risk of heart failure in Finnish men and women

• Published in: Heart (British Cardiac Society) Vol. 97; no. 1; pp. 44 - 48
• Main Authors: Wang, Yujie, Tuomilehto, Jaakko, Jousilahti, Pekka, Antikainen, Riitta, Mähönen, Markku, Männistö, Satu, Katzmarzyk, Peter T, Hu, Gang
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group Ltd and British Cardiovascular Society 01.01.2011; BMJ Publishing Group; BMJ Publishing Group LTD
• Subjects: Adult; Aged; Alcohol; Biological and medical sciences; Blood pressure; Blood Pressure - physiology; Body Mass Index; Caffeine; Cardiology. Vascular system; Cardiovascular disease; Coffee; Coffee - adverse effects; Commuting; Consumption; Diabetes; Diabetes Mellitus, Type 2 - epidemiology; Epidemiologic Methods; epidemiology; Family medical history; Female; Finland - epidemiology; Health risk assessment; Heart; Heart attacks; Heart failure; Heart Failure - epidemiology; Heart Failure - physiopathology; Heart failure, cardiogenic pulmonary edema, cardiac enlargement; Hospitals; Humans; incidence; Insulin; Leisure; Male; Medical sciences; Mens health; Middle Aged; Mortality; Population; Questionnaires; Smoking - epidemiology; Studies; Tea; Womens health; Europe; Finland; Consumption; Human; Heart failure; Cardiovascular disease; Male; Risk; Coffee; Heart disease; Risk factor; Female; Finnish; Circulatory system; Cardiology; Woman
• ISSN: 1355-6037; 1468-201X
• DOI: 10.1136/hrt.2010.206045

ObjectivesTo evaluate the association of coffee consumption with the risk of heart failure (HF) in the Finnish population.DesignProspective population-based cohort study.SettingThis study, which is a part of FINRISK study, was carried out in Finland.SubjectsStudy cohorts included 59 490 Finnish participants aged 25–74 years who were free of HF at baseline.Main outcome measuresHF (2020 men and 1807 women) during a mean follow-up of 19.2 years.ResultsMultivariable-adjusted (age, study year, body mass index, smoking, education, alcohol consumption, tea consumption, physical activity, systolic blood pressure, history of myocardial infarction, history of valvular heart disease, history of diabetes and total cholesterol) HRs (with 95% CI) of HF associated with the amount of coffee consumption daily (0, 1–2, 3–4, 5–6, 7–9 and ≥10 cups) were 1.00, 0.91 (0.71 to 1.16), 0.88 (0.70 to 1.10), 0.91 (0.73 to 1.13), 0.96 (0.76 to 1.22) and 1.02 (0.80 to 1.30) (ptrend=0.485) for men and 1.00, 0.73 (0.56 to 0.97), 0.77 (0.60 to 0.98), 0.68 (0.53 to 0.88), 0.80 (0.61 to 1.04) and 0.88 (0.65 to 1.19) (ptrend=0.007) for women, respectively. Stratification by age, smoking status, alcohol consumption, history of type 2 diabetes mellitus and body mass index gave similar results.ConclusionCoffee consumption does not increase the risk of HF in Finnish men and women. In women, an inverse association was observed between low to moderate coffee consumption and the risk of HF.