Investigation and management of hypercalcaemia in children

Hypercalcaemia is a far less common finding in children than in adults. It may present with characteristic symptoms or may be identified as a coincidental finding in children investigated for a variety of complaints. Assessment of hypercalcaemia requires an understanding of the normal physiological...

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Bibliographic Details
Published inArchives of Disease in Childhood Vol. 97; no. 6; pp. 533 - 538
Main Authors Davies, Justin H, Shaw, Nicholas J
Format Journal Article Book Review
LanguageEnglish
Published London BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health 01.06.2012
BMJ Publishing Group
BMJ Publishing Group Ltd
BMJ Publishing Group LTD
Subjects
Adult
Biological and medical sciences
Calcium
Calcium - blood
Calcium - metabolism
Care and treatment
Causes of
Child
Child Health
General aspects
Health risk assessment
Homeostasis
Humans
Hypercalcemia
Hypercalcemia - diagnosis
Hypercalcemia - etiology
Hypercalcemia - physiopathology
Hypercalcemia - therapy
Individualized Instruction
Medical case management
Medical sciences
Methods
Miscellaneous
Pain
Parathyroid Hormone - blood
Parathyroid Hormone - physiology
Prevention and actions
Public health. Hygiene
Public health. Hygiene-occupational medicine
Vitamin D - analogs & derivatives
Vitamin D - physiology
United Kingdom
Human
Hypercalcemia
Pediatrics
Hydroelectrolytic balance disorder
Metabolic disorder
Clinical management
Treatment
Calcium
Management
Inorganic element
Child
Public health
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Summary:Hypercalcaemia is a far less common finding in children than in adults. It may present with characteristic symptoms or may be identified as a coincidental finding in children investigated for a variety of complaints. Assessment of hypercalcaemia requires an understanding of the normal physiological regulation of plasma calcium by the combined actions of parathyroid hormone, 1,25-dihydroxyvitamin D3 and the calcium sensing receptor. Hypercalcaemia will usually require treatment using a number of different modalities but occasionally it can be due to a benign asymptomatic condition that requires no intervention. This article presents a logical approach to the investigation and subsequent management of this condition.
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ISSN:0003-9888
1468-2044
DOI:10.1136/archdischild-2011-301284