Nanocrystal technology in the delivery of poorly soluble drugs: an overview

Extensive attempts to overcome problems related to solubility of drugs for maximizing bioavailability at targeted sites in the body have been made. The issue of drug solubility appears to attract the continued interest of pharmaceutical manufacturers. In this context, nanocrystallization has emerged...

Full description

Saved in:
Bibliographic Details
Published inCurrent drug delivery Vol. 8; no. 4; p. 398
Main Authors Nagarwal, Ramesh C, Kumar, Rakesh, Dhanawat, Meenakshi, Das, Nirupam, Pandit, J K
Format Journal Article
LanguageEnglish
Published United Arab Emirates 01.07.2011
Subjects
Biological Availability
Chemistry, Pharmaceutical
Drug Delivery Systems - methods
Humans
Nanoparticles - administration & dosage
Nanoparticles - chemistry
Nanotechnology - methods
Pharmaceutical Preparations - administration & dosage
Pharmaceutical Preparations - chemistry
Solubility
Technology, Pharmaceutical - methods
Online AccessGet more information

Cover

More Information
Summary:Extensive attempts to overcome problems related to solubility of drugs for maximizing bioavailability at targeted sites in the body have been made. The issue of drug solubility appears to attract the continued interest of pharmaceutical manufacturers. In this context, nanocrystallization has emerged as an important tool. In the present review, the authors discuss the advantages of nanocrystallized drugs and examine the products available in the market as well as drugs in the pipeline using nanocrystal-based formulations, which are being developed by pharmaceutical companies for drug delivery.
ISSN:1875-5704
DOI:10.2174/156720111795767988