Nanosuspension Technology: Recent Patents on Drug Delivery and their Characterizations

Nanosuspension has arisen as a remunerative, lucrative as well as a potent approach to improve the solubility and bioavailability of poorly aqueous soluble drug entities. Several challenges are still present in this approach which need more research. The prime aim of this review is to identify such...

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Bibliographic Details
Published inRecent patents on drug delivery & formulation Vol. 13; no. 2; p. 91
Main Authors Goel, Surya, Sachdeva, Monika, Agarwal, Vijay
Format Journal Article
LanguageEnglish
Published United Arab Emirates 2019
Subjects
Biological Availability
Chemistry, Pharmaceutical - methods
Drug Delivery Systems
Humans
Nanoparticles
Patents as Topic
Pharmaceutical Preparations - administration & dosage
Pharmaceutical Preparations - chemistry
Solubility
Suspensions
Technology, Pharmaceutical - methods
nanosuspension technology
dosing frequency
drug moieties
solubility
Nanosuspension
bioavailability
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Summary:Nanosuspension has arisen as a remunerative, lucrative as well as a potent approach to improve the solubility and bioavailability of poorly aqueous soluble drug entities. Several challenges are still present in this approach which need more research. The prime aim of this review is to identify such challenges that can be rectified in the future. Through this review, we enlighten the recent patents and advancement in nanosuspension technology that utilize the different drug moieties, instruments and characterization parameters. Nanosuspension has been found to possess great potential to rectify the several issues related to poor bioavailability, site-specific drug delivery, dosing frequency, etc. In the past decade, nanosuspension approach has been complementarily utilized to solve the developed grievances, arisen from poorly soluble drugs. But this field still needs more attention to new discoveries. Nanosuspension contributes a crucial role in administering the different drug entities through a variety of routes involving oral, transdermal, ocular, parenteral, pulmonary, etc. with solving the different issues. This review also confirms the significance of nanosuspension in safety, efficacy, and communal as well as the economic expense associated with healthcare.
ISSN:2212-4039
DOI:10.2174/1872211313666190614151615