Growth in haemophilic boys after HIV infection

• Published in: Archives of disease in childhood Vol. 65; no. 1; pp. 115 - 118
• Main Authors: Pasi, K J, Collins, M A, Ewer, A K, Hill, F G
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health 01.01.1990; BMJ; BMJ Publishing Group Ltd; BMJ Publishing Group LTD
• Subjects: Adolescent; AIDS/HIV; Biological and medical sciences; Blood transfusion; Body Height; Body Weight; Care and treatment; Child; Cohort Studies; Complications; Growth; Growth patterns; Hematologic and hematopoietic diseases; Hemophilia; Hemophilia A - complications; Hemophilia A - physiopathology; Hemophilia in children; HIV; HIV infection; HIV infections; HIV patients; HIV Seropositivity - complications; Human immunodeficiency virus; Humans; Male; Medical sciences; Pediatric diseases; Pediatrics; Platelet diseases and coagulopathies; Seroconversion; Weight; Human; Immunopathology; Seropositivity; Transfusion; Factor VIII; AIDS; Hemopathy; Hemophilia A; Infection; Concomitant disease; Viral disease; Complication; Somatic growth; Child; Coagulation factor; Coagulopathy
• ISSN: 0003-9888; 1468-2044
• DOI: 10.1136/adc.65.1.115

Although failure to thrive has been documented as a major problem in babies with congenital HIV infection, there is little information on whether HIV affects growth in older children who become infected with HIV. The growth of 27 haemophilic boys, in whom HIV seroconversion was recorded between 1981 and 1986, has been assessed to see if the pattern changed after seroconversion. Height and weight recordings were analysed over a mean period of 9.2 years with a mean duration from HIV seroconversion of 4.5 years (range 2 to 6 years). Height standard deviation scores and ratio of weight to 50th centile for chronological age were calculated. No significant change in growth pattern as judged by height and weight has been observed within this group of boys after HIV seroconversion. Growth assessment continues to be evaluated to see if further progression of HIV disease changes growth pattern in these boys.