Propranolol in acute intermittent porphyria

Twenty cases of acute intermittent porphyria were studied during the acute phase. Cardiovascular manifestations were noted in all the cases, with tachycardia in 20 and with hypertension in 17. Propranolol in doses ranging from 20--200 mg was given to all the cases and produced adequate control of ta...

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Bibliographic Details
Published inPostgraduate medical journal Vol. 55; no. 646; pp. 546 - 547
Main Authors Menawat, A. S., Panwar, R. B., Kochar, D. K., Joshi, C. K.
Format Journal Article
LanguageEnglish
Published England The Fellowship of Postgraduate Medicine 01.08.1979
Oxford University Press
BMJ Group
Subjects
Acute Disease
Blood Pressure - drug effects
Drug Administration Schedule
Heart Rate - drug effects
Humans
Porphyrias - drug therapy
Porphyrias - physiopathology
Propranolol - administration & dosage
Propranolol - therapeutic use
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Summary:Twenty cases of acute intermittent porphyria were studied during the acute phase. Cardiovascular manifestations were noted in all the cases, with tachycardia in 20 and with hypertension in 17. Propranolol in doses ranging from 20--200 mg was given to all the cases and produced adequate control of tachycardia and hypertension. At follow-up, smaller doses of propranolol were found to maintain the pulse rate and BP within normal limits and also to prevent acute attacks.
Bibliography:ark:/67375/NVC-H15N5JTC-D
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PMID:514931
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ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0032-5473
1469-0756
DOI:10.1136/pgmj.55.646.546