Use of the semiconductor nanotechnologies "quantum dots" for in vivo cancer imaging

Non-invasive in vivo imaging offers great potential to facilitate translational drug development research at the animal testing phase. The emerging luminescent nanoparticles or quantum dots provide a new type of biological agents that can improve these applications. The advantages of luminescent nan...

Full description

Saved in:
Bibliographic Details
Published inRecent patents on anti-cancer drug discovery Vol. 4; no. 3; p. 207
Main Authors Ciarlo, Monica, Russo, Patrizia, Cesario, Alfredo, Ramella, Sara, Baio, Gabriella, Neumaier, Carlo E, Paleari, Laura
Format Journal Article
LanguageEnglish
Published United Arab Emirates 01.11.2009
Subjects
Animals
Fluorometry - methods
Humans
Molecular Imaging - methods
Neoplasms - diagnosis
Quantum Dots
Semiconductors
Xenograft Model Antitumor Assays - methods
Online AccessGet more information

Cover

More Information
Summary:Non-invasive in vivo imaging offers great potential to facilitate translational drug development research at the animal testing phase. The emerging luminescent nanoparticles or quantum dots provide a new type of biological agents that can improve these applications. The advantages of luminescent nanoparticles for biological applications include their high quantum yield, color availability, good photo-stability, large surface-to-volume ratio, surface functionality, and small size. These properties could improve the sensitivity of biological detection and imaging by at least 10- to 100-fold and make them an exceptional tool for live-cell imaging. In this review patents on applications of semiconductor quantum dots for in vivo imaging are discussed.
ISSN:2212-3970
DOI:10.2174/157489209789206841