Adrenocortical oncocytoma

• Published in: Journal of clinical pathology Vol. 52; no. 2; pp. 151 - 153
• Main Authors: Kitching, P A, Patel, V, Harach, H R
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group Ltd and Association of Clinical Pathologists 01.02.1999; BMJ
• Subjects: Adenoma, Oxyphilic - diagnostic imaging; Adenoma, Oxyphilic - pathology; Adrenal Cortex Neoplasms - diagnostic imaging; Adrenal Cortex Neoplasms - pathology; Adrenals. Adrenal axis. Renin-angiotensin system (diseases); Aged; Biological and medical sciences; Endocrinopathies; Female; Humans; Medical sciences; Non tumoral diseases. Target tissue resistance. Benign neoplasms; Tomography, X-Ray Computed; Endocrinopathy; Human; Immunohistochemistry; Adrenal cortex diseases; Radiodiagnosis; Adrenal cortex; Case study; Pathology; Oncocytoma; Medical imagery; Tumor; Female; Computerized axial tomography; Molecular biology; Elderly
• ISSN: 0021-9746; 1472-4146
• DOI: 10.1136/jcp.52.2.151

The histopathology and ultrastructural features of an adrenocortical oncocytoma are reported. The tumour was discovered incidentally during investigation for hypertension in a 72 year old female. Oncocytic tumours of the adrenal cortex are rare, with only 20 examples described in English language reports. Most have been non-functioning and benign, like the present example. Molecular studies may help assess the significance of oncocytic change in the pathogenesis and behaviour of oncocytic neoplasms.