Easy as 1, 2, 3? Histamine receptors and gastric acid

NAMH was detected in the gastric juice of 5/7 H pylori positive and 0/9 H pylori negative subjects using gas chromatography-mass spectrophotometry, 19 but in contrast with Courillion-Mallet and colleagues, 11 it was not detected in either H pylori positive gastric biopsies or cultures of H pylori. [...

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Bibliographic Details
Published inGut Vol. 50; no. 6; pp. 747 - 748
Main Author Beales, I L P
Format Journal Article
LanguageEnglish
Published England BMJ Publishing Group Ltd and British Society of Gastroenterology 01.06.2002
BMJ Publishing Group LTD
Copyright 2002 by Gut
Subjects
Acids
allelic association
Animals
Chinese hamster ovary cells
colorectal cancer
Cricetinae
environmental carcinogens
Gastric Acid - metabolism
Histamine
Histamine - metabolism
histamine H2 receptors
histamine H3 receptors
Kinases
N-alpha-methyl-histamine
Physiology
Receptors, Histamine - physiology
Rodents
Studies
UGT1A gene locus
UGT1A7
xenobiotic metabolism
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Summary:NAMH was detected in the gastric juice of 5/7 H pylori positive and 0/9 H pylori negative subjects using gas chromatography-mass spectrophotometry, 19 but in contrast with Courillion-Mallet and colleagues, 11 it was not detected in either H pylori positive gastric biopsies or cultures of H pylori. [...]the physiological role of histamine receptors in the stomach does not appear to be the simple balance outlined by Saitoh et al.
Bibliography:istex:ED4CAD59CEC8634214307CE3413A1A4E32A18E36
PMID:12010870
ark:/67375/NVC-58PP0HK8-R
N-alpha-methyl-histamine, which is produced in the gastric mucosa by Helicobacter pylori, is a potent H2 receptor agonist as well as a H3 receptor agonist
local:0500747
href:gutjnl-50-747.pdf
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Commentary-1
ISSN:0017-5749
1468-3288
1458-3288
DOI:10.1136/gut.50.6.747