Insulin-like growth factor type 1—friend or foe?

[...]patients chronically exposed to high levels of glucose may adapt to conditions by the regulatory processes relating to this and the rapid normalisation of blood glucose concentration may not allow for the restoration of a "non-adapted response".

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Bibliographic Details
Published inBritish journal of ophthalmology Vol. 82; no. 7; pp. 719 - 720
Main Author KNOTT, RACHEL M
Format Journal Article
LanguageEnglish
Published BMA House, Tavistock Square, London, WC1H 9JR BMJ Publishing Group Ltd 01.07.1998
BMJ Publishing Group LTD
Subjects
Bioavailability
Blood Glucose - metabolism
Cell growth
Diabetes
Diabetic retinopathy
Diabetic Retinopathy - metabolism
Diabetic Retinopathy - therapy
Glucose
Humans
Insulin
Insulin - metabolism
Insulin - therapeutic use
Insulin resistance
Insulin-Like Growth Factor I - adverse effects
Insulin-Like Growth Factor I - physiology
Insulin-Like Growth Factor I - therapeutic use
Insulin-like growth factors
Metabolism
Recombinant Proteins - therapeutic use
Studies
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Summary:[...]patients chronically exposed to high levels of glucose may adapt to conditions by the regulatory processes relating to this and the rapid normalisation of blood glucose concentration may not allow for the restoration of a "non-adapted response".
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PMID:9924357
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href:bjophthalmol-82-719.pdf
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ObjectType-Editorial-2
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ISSN:0007-1161
1468-2079
DOI:10.1136/bjo.82.7.719