Correspondence to ‘Hypersensitivity reactions with allopurinol and febuxostat: a study using the Medicare claims data’

We read with great interest the article by Singh and Cleveland, which the authors reported that the observed hypersensitivity reactions (HSRs) associated with allopurinol and febuxostat were not different.1 This conclusion differs from previous studies on HSRs associated with allopurinol and febuxos...

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Bibliographic Details
Published inAnnals of the rheumatic diseases Vol. 81; no. 6; p. e107
Main Authors Ma, Kevin Sheng-Kai, Wei, James Cheng-Chung, Chung, Wen-Hung
Format Journal Article
LanguageEnglish
Published England BMJ Publishing Group Ltd and European League Against Rheumatism 01.06.2022
Elsevier Limited
Subjects
Aged
Algorithms
Allergens
Allopurinol
Allopurinol - adverse effects
Anaphylaxis
Anti-inflammatory agents
Causality
Correspondence
Dermatitis
Drug dosages
Eosinophilia
epidemiology
Erythema
Erythema multiforme
Febuxostat - adverse effects
gout
Gout - drug therapy
Gout Suppressants - adverse effects
Humans
Hypersensitivity (delayed)
Hyperuricemia - drug therapy
Medicare
Nonsteroidal anti-inflammatory drugs
Patients
pharmacogenetics
pharmacokinetics
Stevens-Johnson syndrome
Toxic epidermal necrolysis
United States
United States
Taiwan
pharmacokinetics
epidemiology
pharmacogenetics
gout
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Summary:We read with great interest the article by Singh and Cleveland, which the authors reported that the observed hypersensitivity reactions (HSRs) associated with allopurinol and febuxostat were not different.1 This conclusion differs from previous studies on HSRs associated with allopurinol and febuxostat using claimed data2 and intramural databases.3 The discrepancy may arise from different inclusion criteria for the diagnosis of HSRs based on International Classification of Diseases, Ninth Revision (ICD-9) coding system, methods for identifying causative drugs, methods for stratification, as well as ethnicity of the involved population.
Bibliography:SourceType-Scholarly Journals-1
ObjectType-Correspondence-2
content type line 14
ObjectType-Letter to the Editor-1
ObjectType-Correspondence-1
ObjectType-Commentary-2
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ISSN:0003-4967
1468-2060
1468-2060
DOI:10.1136/annrheumdis-2020-218090