Chipping away at 'stemness'

Global gene-expression analyses of human embryonic stem cells confirm the involvement of some known genes in stem-cell function and identify some new candidate regulators of stem-cell growth. Support remains elusive, however, for the concept of 'stemness'--a pattern of expression of genes...

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Bibliographic Details
Published inGenome biology Vol. 5; no. 8; p. 235
Main Authors Pyle, April D, Donovan, Peter J, Lock, Leslie F
Format Journal Article
LanguageEnglish
Published England BioMed Central Ltd 01.01.2004
BioMed Central
Subjects
Cell Differentiation - genetics
Embryo, Mammalian - cytology
Embryo, Mammalian - metabolism
Gene Expression Profiling
Genomics
Humans
Minireview
Stem Cells - cytology
Stem Cells - metabolism
Transcription, Genetic - genetics
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Summary:Global gene-expression analyses of human embryonic stem cells confirm the involvement of some known genes in stem-cell function and identify some new candidate regulators of stem-cell growth. Support remains elusive, however, for the concept of 'stemness'--a pattern of expression of genes that is common to all stem cells.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1465-6906
1474-760X
1465-6914
DOI:10.1186/gb-2004-5-8-235