Factors Affecting the Metabolite Productions in Endophytes: Biotechnological Approaches for Production of Metabolites

Since 1980, many species and different strains from endophytic genera of Phomopsis, Fusarium, Pestaliopsis and Aspergillus have been studied because of their ability to produce medicinal compounds found in their host plants. Some of these medicinal agents such as Taxol, Brefeldine A, Camptothecin an...

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Bibliographic Details
Published inCurrent medicinal chemistry Vol. 27; no. 11; p. 1855
Main Authors Morales-Sánchez, Viridiana, Fe Andrés, Maria, Díaz, Carmen Elisa, González-Coloma, Azucena
Format Journal Article
LanguageEnglish
Published United Arab Emirates 01.01.2020
Subjects
Endophytes
biotechnology
secondary metabolites
medicinal compounds
drugs
anticancer
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Summary:Since 1980, many species and different strains from endophytic genera of Phomopsis, Fusarium, Pestaliopsis and Aspergillus have been studied because of their ability to produce medicinal compounds found in their host plants. Some of these medicinal agents such as Taxol, Brefeldine A, Camptothecin and Podophyllotoxin are being produced in large-scale after an optimization process. However, the potential of fungal endophytes to produce host-like medicinal compounds remains largely unexplored.
ISSN:1875-533X
DOI:10.2174/0929867326666190626154421