Nanotherapeutics for the Treatment of Cancer and Arthritis

• Published in: Current drug metabolism Vol. 20; no. 6; p. 430
• Main Authors: Patel, Pal, Meghani, Nikita, Kansara, Krupa, Kumar, Ashutosh
• Format: Journal Article
• Language: English
• Published: Netherlands 01.01.2019
• Subjects: Arthritis - drug therapy; Drug Delivery Systems - methods; Humans; Lipids; Liposomes; Metal Nanoparticles; Micelles; Nanomedicine - methods; Nanoparticles - therapeutic use; Nanotechnology; Neoplasms - drug therapy; Polymers; breast cancer; cancer; head and neck cancer; rheumatoid arthritis; Nanotechnology; nanocarriers
• ISSN: 1875-5453
• DOI: 10.2174/1389200220666181127102720

Nanotechnology is gaining significant attention worldwide for the treatment of complex diseases such as AIDS (acquired immune deficiency syndrome), cancer and rheumatoid arthritis. Nanomedicine is the application of nanotechnology used for diagnosis and treatment for the disease that includes the preservation and improvement of human health by covering an area such as drug delivery using nanocarriers, nanotheranostics and nanovaccinology. The present article provides an insight into several aspects of nanomedicine such as usages of multiple types of nanocarriers, their status, advantages and disadvantages with reference to cancer and rheumatoid arthritis. An extensive search was performed on the bibliographic database for research article on nanotechnology and nanomedicine along with looking deeply into the aspects of these diseases, and how all of them are co-related. We further combined all the necessary information from various published articles and briefed to provide the current status. Nanomedicine confers a unique technology against complex diseases which includes early diagnosis, prevention, and personalized therapy. The most common nanocarriers used globally are liposomes, polymeric nanoparticles, dendrimers, metallic nanoparticles, magnetic nanoparticles, solid lipid nanoparticles, polymeric micelles and nanotubes among others. Nanocarriers are used to deliver drugs and biomolecules like proteins, antibody fragments, DNA fragments, and RNA fragments as the base of cancer biomarkers.