Heparin therapy in giant cell arteritis

Colour Doppler imaging is an ultrasonic imaging modality that combines B-mode ultrasonography with Doppler ultrasonography. The sequence of rapid improvement of orbital CDI haemodynamics, visual acuity, and visual field strongly suggest that the administration of heparin was responsible. Since this...

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Bibliographic Details
Published inBritish journal of ophthalmology Vol. 88; no. 2; pp. 298 - 301
Main Authors Buono, L M, Foroozan, R, de Virgiliis, M, Savino, P J
Format Journal Article
LanguageEnglish
Published BMA House, Tavistock Square, London, WC1H 9JR BMJ Publishing Group Ltd 01.02.2004
BMJ Publishing Group LTD
Copyright 2004 British Journal of Ophthalmology
Subjects
Aged
Aged, 80 and over
Anticoagulants - therapeutic use
Biopsy
Defects
Drug Therapy, Combination
giant
Giant Cell Arteritis - drug therapy
Glucocorticoids - therapeutic use
heparin
Heparin - therapeutic use
Humans
Letter
Macular degeneration
Male
Patients
Smooth muscle
Ultrasonic imaging
Veins & arteries
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Summary:Colour Doppler imaging is an ultrasonic imaging modality that combines B-mode ultrasonography with Doppler ultrasonography. The sequence of rapid improvement of orbital CDI haemodynamics, visual acuity, and visual field strongly suggest that the administration of heparin was responsible. Since this occurred rapidly, some of the biochemical activities of heparin, such as inhibition of smooth muscle cell hypertrophy and the others that act on a more chronic time line could not have caused improvement.
Bibliography:href:bjophthalmol-88-298.pdf
local:0880298
istex:1E10A1B2AB2517903CA2CA4541EA44B10C508732
Correspondence to: Dr Lawrence M Buono Duke University Eye Center, Erwin Road, Box 3802, Durham, NC 27710, USA; buono001@mc.duke.edu
PMID:14736795
ark:/67375/NVC-4JWWW1RK-P
Originally presented in part at the 28th Annual North American Neuro-Ophthalmology Society (NANOS) Meeting in Copper Mountain Resort, CO, USA, 9–14 February, 2002.
Correspondence to: …Dr Lawrence M Buono …Duke University Eye Center, Erwin Road, Box 3802, Durham, NC 27710, USA; buono001@mc.duke.edu
ISSN:0007-1161
1468-2079
DOI:10.1136/bjo.2003.021592