Solitary fibrous tumour of mediastinum: an often asymptomatic neoplasm

Solitary fibrous tumours (SFTs) are rare neoplasms derived from mesenchymal cell lines. They are often asymptomatic, follow an indolent growth pattern and are more often benign than malignant. Here, we present a case of a very large, asymptomatic mediastinal SFT in an otherwise healthy man. A 67-yea...

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Published inBMJ case reports Vol. 14; no. 8; p. e241223
Main Authors Sexton, Gerard, McLoughlin, Joseph, Burke, Louise, Doddakula, Kishore
Format Journal Article
LanguageEnglish
Published England BMJ Publishing Group LTD 13.08.2021
BMJ Publishing Group
Subjects
Aged
Asymptomatic
Biopsy
Case Report
Case reports
Diaphragm (Anatomy)
Gene expression
Histology
Humans
Lung cancer
Male
Mediastinum
Ostomy
Radiography
Sarcoma
Solitary Fibrous Tumors - diagnostic imaging
Solitary Fibrous Tumors - surgery
Surgery
Thorax
Tumors
X-rays
cardiothoracic surgery
lung cancer (oncology)
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Summary:Solitary fibrous tumours (SFTs) are rare neoplasms derived from mesenchymal cell lines. They are often asymptomatic, follow an indolent growth pattern and are more often benign than malignant. Here, we present a case of a very large, asymptomatic mediastinal SFT in an otherwise healthy man. A 67-year-old Irish man was referred for workup of an asymptomatic murmur. Auscultation of the lung fields revealed diminished breath sounds on the right side. Chest X-ray identified a 20 cm mass localised within the thorax. CT of the thorax confirmed a pleural based, solid lesion with no local invasion. CT-guided core biopsies were reported as consistent with SFT. Primary excision of the lesion was undertaken via median sternotomy. Histological examination confirmed a diagnosis of SFT. The patient remains well at this time. Primary excisive surgery is a safe and effective treatment modality for SFTs.
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ISSN:1757-790X
1757-790X
DOI:10.1136/bcr-2020-241223