PROPRANOLOL AND THE UTILIZATION OF RADIOIODINE BY THE HUMAN THYROID GLAND

ABSTRACT The effect of propranolol on radioiodine utilization by the thyroid gland has been studied in 18 patients. All parameters of iodine uptake by the thyroid – initial 5–20 minutes after intravenous administration, 2, 4, 24 and 48 hours after oral administration were unaltered by propranolol ad...

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Bibliographic Details
Published inActa endocrinologica (Copenhagen) Vol. 61; no. 3; pp. 393 - 399
Main Authors Hadden, D R, Bell, T K, McDevitt, D G, Shanks, R G, Montgomery, D A, Weaver, J A
Format Journal Article
LanguageEnglish
Published Denmark 01.07.1969
Subjects
Humans
Hyperthyroidism - drug therapy
Iodine - metabolism
Iodine Radioisotopes
Propranolol - pharmacology
Thyroid Function Tests
Thyroid Gland - drug effects
Thyroid Gland - metabolism
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Summary:ABSTRACT The effect of propranolol on radioiodine utilization by the thyroid gland has been studied in 18 patients. All parameters of iodine uptake by the thyroid – initial 5–20 minutes after intravenous administration, 2, 4, 24 and 48 hours after oral administration were unaltered by propranolol administration. In three of four patients studied an increase in isotopically labelled serum PBI was observed after 8 days propranolol therapy.
ISSN:0804-4643
0001-5598
1479-683X
DOI:10.1530/acta.0.0610393