Urinary kallikrein activity of workers exposed to lead

Two groups of men of different age ranges and with the same period of lead exposure were selected for study in a recently opened car-battery factory. Two other groups of age-matched men, not exposed to heavy metals in their work, were used as controls. Morning urines were collected from control and...

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Bibliographic Details
Published inBritish Journal of Industrial Medicine Vol. 35; no. 3; pp. 226 - 229
Main Authors Boscolo, P, Porcelli, G, Cecchetti, G, Salimei, E, Iannaccone, A
Format Journal Article
LanguageEnglish
Published England BMJ Publishing Group Ltd 01.08.1978
British Medical Association
BMJ Publishing Group LTD
Subjects
Adult
Age Factors
Aminolevulinic Acid - urine
Biochemistry
Environmental Exposure
Enzymes
Excretion
Humans
Hypertension
Kallikreins - urine
Kidneys
Lead
Lead - urine
Lead industry
Lead poisoning
Male
Middle Aged
Occupational Medicine
Urine
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Summary:Two groups of men of different age ranges and with the same period of lead exposure were selected for study in a recently opened car-battery factory. Two other groups of age-matched men, not exposed to heavy metals in their work, were used as controls. Morning urines were collected from control and exposed groups for determination of urinary kallikrein activity, urinary delta-amino-levulinic acid (ALA) and lead levels. The environmental lead levels and the urinary ALA and lead values indicated that exposure in the factory was not heavy. The older group of lead-exposed workers showed greatly reduced urinary kallikrein activity compared with that of the age-matched controls. In contrast, the younger group did not show any significant alteration in urinary kallikrein excretion.
Bibliography:ark:/67375/NVC-NVFQ86FD-4
href:oemed-35-226.pdf
istex:AEC7FA3D146ABEE8DDF0A96D150927CED1C9BF5E
local:oemed;35/3/226
PMID:698136
ISSN:0007-1072
1351-0711
1470-7926
DOI:10.1136/oem.35.3.226