Serum anti-Müllerian hormone concentrations before and after treatment of an ovarian granulosa cell tumour in a cat

A 15-year-old female cat was presented for investigation of progressive behavioural changes, polyuria, polydipsia and periuria. An ovarian granulosa cell tumour was identified and the cat underwent therapeutic ovariohysterectomy (OHE). The cat’s clinical signs resolved, but 6 months later it was dia...

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Bibliographic Details
Published inJFMS open reports Vol. 3; no. 2; pp. 2055116917722701 - 2055116917722705
Main Authors Heaps, Laura A, Scudder, Christopher J, Lipscomb, Vicky J, Steinbach, Sarah ML, Priestnall, Simon L, Martineau, Henny, Szladovits, Balazs, Fowkes, Robert C, Garden, Oliver A
Format Journal Article
LanguageEnglish
Published Sage UK: London, England SAGE Publications 01.07.2017
Sage Publications Ltd
SAGE Publishing
Subjects
Case Report
Ovarian cancer
Ovaries
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Summary:A 15-year-old female cat was presented for investigation of progressive behavioural changes, polyuria, polydipsia and periuria. An ovarian granulosa cell tumour was identified and the cat underwent therapeutic ovariohysterectomy (OHE). The cat’s clinical signs resolved, but 6 months later it was diagnosed as having an anaplastic astrocytoma and was euthanased. Serum anti-Müllerian hormone (AMH) concentration prior to OHE was increased vs a control group of entire and neutered female cats. Following OHE, serum AMH concentration decreased to <1% of the original value. Serum AMH measurement may represent a novel diagnostic and monitoring tool for functional ovarian neoplasms in cats.
ISSN:2055-1169
2055-1169
DOI:10.1177/2055116917722701