Staphylococcus aureus pneumonia and dengue virus co-infection and review of implications of coinfection

• Published in: BMJ case reports Vol. 2012; no. jul02 1; p. bcr0220125804
• Main Authors: Nagassar, Rajeev Peeyush, Bridgelal-Nagassar, Roma Jaanki, McMorris, Nathalie, Judith Roye-Green, Karen
• Format: Journal Article
• Language: English
• Published: England BMJ Publishing Group LTD 03.07.2012; BMJ Publishing Group
• Series: Findings that shed new light on the possible pathogenesis of a disease or an adverse effect
• Subjects: Adolescent; Anti-Bacterial Agents - therapeutic use; Antibodies, Viral - blood; Bacterial infections; Black; Blood; Coinfection; Consciousness; Creatinine; Dengue - blood; Dengue - complications; Dengue - therapy; Dengue fever; Dengue Virus - immunology; Findings That Shed New Light on the Possible Pathogenesis of a Disease or an Adverse Effect; Hepatitis; Humans; Infections; Leukocytes; Male; Patients; Pneumonia; Pneumonia - complications; Pneumonia - drug therapy; Pneumonia - microbiology; South/Central America; Staphylococcus aureus
• ISSN: 1757-790X; 1757-790X
• DOI: 10.1136/bcr.02.2012.5804

Dengue fever is an important public health problem in Jamaica and has various serious manifestations, which if not identified and treated at the appropriate time can lead to dire consequences. Bacterial co-infections have been seen in clinical practice but may be thought of as simply coincidental. This review highlights the importance of bacteria in exacerbating dengue infections and the importance of looking for co-infection in patients with certain clinical manifestations. It also provides the reader with a scientific understanding of the immune pathogenesis of dengue and bacterial co-infections.