Chemical and medicinal versatility of dithiocarbamates: an overview

Dithiocarbamates are considered as the simplest occurring organosulfur compounds exhibiting diverse chemical and medicinal versatility. Dithiocarbamates have been used as pesticide in the 20(th) century but thereafter they have attracted the interest of medicinal chemists due to their metal binding...

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Bibliographic Details
Published inMini reviews in medicinal chemistry Vol. 14; no. 12; p. 1021
Main Authors Bala, Veenu, Gupta, Gopal, Sharma, Vishnu L
Format Journal Article
LanguageEnglish
Published Netherlands 01.01.2014
Subjects
Animals
Anti-HIV Agents - chemical synthesis
Anti-HIV Agents - chemistry
Anti-HIV Agents - pharmacology
Antifungal Agents - chemical synthesis
Antifungal Agents - chemistry
Antifungal Agents - pharmacology
Antineoplastic Agents - chemical synthesis
Antineoplastic Agents - chemistry
Antineoplastic Agents - pharmacology
Drug Discovery
HIV - drug effects
Humans
Mycoses - drug therapy
Neoplasms - drug therapy
Spermatocidal Agents - chemical synthesis
Spermatocidal Agents - chemistry
Spermatocidal Agents - pharmacology
Thiocarbamates - chemical synthesis
Thiocarbamates - chemistry
Thiocarbamates - pharmacology
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Summary:Dithiocarbamates are considered as the simplest occurring organosulfur compounds exhibiting diverse chemical and medicinal versatility. Dithiocarbamates have been used as pesticide in the 20(th) century but thereafter they have attracted the interest of medicinal chemists due to their metal binding capacity. Recently a variety of chemical and medicinal properties of dithiocarbamates have been explored other than metal binding capacity. This review collectively describes the most significant chemical and medicinal properties of dithiocarbamate derivatives reported over the last decade.
ISSN:1875-5607
DOI:10.2174/1389557514666141106130146