Eugenol as a Potential Drug Candidate: A Review

Eugenol is a bioactive compound widely available in many herbs like clove, cinnamon, tulsi, pepper etc. The compound is known for its antioxidant, antimicrobial, anesthetic, anti-inflammatory, neuroprotective, anti-diabetic, and anti-cancer activities. In pharmaceutical analysis, eugenol is used as...

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Published inCurrent topics in medicinal chemistry Vol. 21; no. 20; p. 1804
Main Authors Taleuzzaman, Mohamad, Jain, Pooja, Verma, Rishabh, Iqbal, Zeenat, Mirza, Mohd Aamir
Format Journal Article
LanguageEnglish
Published United Arab Emirates 01.01.2021
Subjects
Clinical Trials as Topic
Eugenol - adverse effects
Eugenol - isolation & purification
Eugenol - pharmacology
Eugenol - therapeutic use
Humans
Patents as Topic
Analytical techniques
Clinical trials
Patents
Pharmacokinetics
Eugenol
Pharmacological properties
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Summary:Eugenol is a bioactive compound widely available in many herbs like clove, cinnamon, tulsi, pepper etc. The compound is known for its antioxidant, antimicrobial, anesthetic, anti-inflammatory, neuroprotective, anti-diabetic, and anti-cancer activities. In pharmaceutical analysis, eugenol is used as a marker for single drugs and drug products. Dental care, household, and personal hygiene products are other areas where it has established its potential. In the food industry, eugenol is used as a flavouring agent in non-alcoholic beverages, baked foods, and chewing gums. Considering the huge potential of eugenol, this review is an attempt to collate the regulatory information, physico-chemical properties, toxicity profile, marketed conventional and novel formulations, analytical methods, extraction procedures, recent patents and clinical trials of the moiety. Based on literature survey a schematic diagram of mechanism of action has also been made.
ISSN:1873-4294
DOI:10.2174/1568026621666210701141433