Clinical review: liberation from mechanical ventilation

Mechanical ventilation is the defining event of intensive care unit (ICU) management. Although it is a life saving intervention in patients with acute respiratory failure and other disease entities, a major goal of critical care clinicians should be to liberate patients from mechanical ventilation a...

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Bibliographic Details
Published inCritical care (London, England) Vol. 12; no. 4; p. 221
Main Authors El-Khatib, Mohamad F, Bou-Khalil, Pierre
Format Journal Article
LanguageEnglish
Published England National Library of Medicine - MEDLINE Abstracts 01.01.2008
BioMed Central Ltd
BioMed Central
Subjects
Humans
Lung Injury - physiopathology
Lung Injury - prevention & control
Respiration, Artificial - methods
Respiration, Artificial - trends
Respiratory Mechanics - physiology
Review
Treatment Outcome
Ventilator Weaning - methods
Ventilator Weaning - trends
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Summary:Mechanical ventilation is the defining event of intensive care unit (ICU) management. Although it is a life saving intervention in patients with acute respiratory failure and other disease entities, a major goal of critical care clinicians should be to liberate patients from mechanical ventilation as early as possible to avoid the multitude of complications and risks associated with prolonged unnecessary mechanical ventilation, including ventilator induced lung injury, ventilator associated pneumonia, increased length of ICU and hospital stay, and increased cost of care delivery. This review highlights the recent developments in assessing and testing for readiness of liberation from mechanical ventilation, the etiology of weaning failure, the value of weaning protocols, and a simple practical approach for liberation from mechanical ventilation.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1364-8535
1466-609X
DOI:10.1186/cc6959