Defining dysbiosis threatens Koch's postulates and current dogma on the role of Paneth cells in Crohn's disease

[...]genome-wide association studies have revealed a large set of inborn genetic errors in several regulatory factors involved in the maintenance of Paneth cell function. 1 However, it is still not clear whether impaired secretory function of Paneth cell precedes the onset and relapse of Crohn'...

Full description

Saved in:
Bibliographic Details
Published inGut Vol. 65; no. 2; pp. 190 - 191
Main Authors Chamaillard, Mathias, Radulovic, Katarina
Format Journal Article
LanguageEnglish
Published England BMJ Publishing Group LTD 01.02.2016
Subjects
Animals
Crohn Disease - etiology
Crohns disease
Dysbiosis - complications
Experiments
Ileitis - etiology
Intestines - microbiology
Metabolism
Researchers
Small intestine
Studies
IBD MODELS
Online AccessGet full text

Cover

More Information
Summary:[...]genome-wide association studies have revealed a large set of inborn genetic errors in several regulatory factors involved in the maintenance of Paneth cell function. 1 However, it is still not clear whether impaired secretory function of Paneth cell precedes the onset and relapse of Crohn's disease.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Commentary-1
ISSN:0017-5749
1468-3288
DOI:10.1136/gutjnl-2015-309714