Minimally invasive secondary cytoreductive surgery for hepato-renal recess isolated recurrence of serous endometrial cancer in BRCA1 mutated patient

Serous endometrial cancer represents a relatively rare entity, accounting for about 10% of all diagnosed endometrial cancer, but it is responsible for 40% of endometrial cancer-related deaths. Patients with serous endometrial cancer have a higher risk of recurrence and poorer prognosis when compared...

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Published inInternational journal of gynecological cancer Vol. 32; no. 6; pp. 813 - 814
Main Authors Iacobelli, Valentina, Taliente, Francesco, Scambia, Giovanni, Fanfani, Francesco, Giuliante, Felice, Gallotta, Valerio
Format Journal Article
LanguageEnglish
Published England BMJ Publishing Group Ltd 27.04.2022
BMJ Publishing Group LTD
Subjects
BRCA1 Protein
Cancer surgery
Consent
Endometrial cancer
Endometrial Neoplasms
Laparoscopes
Laparoscopy
Medical prognosis
Ovarian cancer
Patients
Surgery
Surgical Oncology
Surgical outcomes
Video article
Laparoscopes
Endometrial Neoplasms
BRCA1 Protein
Surgical Oncology
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Summary:Serous endometrial cancer represents a relatively rare entity, accounting for about 10% of all diagnosed endometrial cancer, but it is responsible for 40% of endometrial cancer-related deaths. Patients with serous endometrial cancer have a higher risk of recurrence and poorer prognosis when compared stage-for-stage with endometrioid endometrial cancer. Serous endometrial cancer shows an aggressive behavior and shares most of its molecular features with high-grade serous ovarian cancer, such as the occurrence of BRCA mutations, whose role in this setting is still not completely understood. 1 2 Moreover, the role of secondary cytoreductive surgery for recurrent disease has not been standardized.3 4
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:1048-891X
1525-1438
DOI:10.1136/ijgc-2021-003271