Skin closUre in carPal tunnEl Release (SUPER): protocol for a blinded randomised controlled trial comparing absorbable and non-absorbable sutures in carpal tunnel release

• Published in: BMJ open Vol. 14; no. 4; p. e082289
• Main Authors: Savolainen, Aukusti, Nietosvaara, Yrjänä, Sirola, Joonas, Hytönen, Mikael, Reito, Aleksi, Heikkinen, Noora, Räisänen, Mikko Petteri
• Format: Journal Article
• Language: English
• Published: England British Medical Journal Publishing Group 16.04.2024; BMJ Publishing Group LTD; BMJ Publishing Group
• Subjects: Carpal tunnel syndrome; Carpal Tunnel Syndrome - surgery; Cicatrix; Clinical Trial; Hand & wrist; Hand surgery; Humans; Pain; Patient Reported Outcome Measures; Patient Satisfaction; Randomized Controlled Trials as Topic; Scars; Steroids; Surgeons; Surgery; Sutures; Treatment Outcome; Clinical Trial; Hand & wrist; Patient Reported Outcome Measures; Patient Satisfaction
• ISSN: 2044-6055; 2044-6055
• DOI: 10.1136/bmjopen-2023-082289

IntroductionCarpal tunnel syndrome is a common disorder affecting a substantial portion of the general population. Surgical intervention is often deemed necessary, with the median nerve release being one of the most frequent operations. Optimising all the aspects of this procedure can enhance patient satisfaction with the treatment.Methods and analysisWe aim to determine the differences in the aesthetic outcome of the scar as well as the pain experienced during the healing process between the use of absorbable and non-absorbable sutures. The primary outcome measure will be the patients’ subjective satisfaction with the aesthetic appearance of the scar 1 year after the operation. Secondary outcomes will include a similar evaluation of the aesthetics performed by a blinded outcome assessor, as well as pain experienced by the patients during the 2 weeks postoperatively. The severity and improvement of the patients’ symptoms will also be measured by a Finnish version of the Boston Carpal Tunnel Questionnaire. Costs will be evaluated for both groups. Safety of the wound closure will be followed and reported.Ethics and disseminationThis protocol was approved by the Research Ethics Committee of the Northern Savo Hospital District (2319/2021). The trial will be conducted in accordance with the principles of Good Clinical Practice and the Declaration of Helsinki. The results will be disseminated through publication in peer-reviewed journals.Trial registration number NCT05503719.