Effects of non-shunting operation on azygos venous blood flow in cirrhotic patients

• Published in: Gut Vol. 30; no. 10; pp. 1396 - 1400
• Main Authors: Kokudo, N, Kawasaki, S, Ohashi, K, Sakamoto, H, Koyama, H, Sanjo, K, Idezuki, Y
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group Ltd and British Society of Gastroenterology 01.10.1989; BMJ; BMJ Publishing Group LTD
• Subjects: Adult; Aged; Azygos Vein - physiopathology; Biological and medical sciences; Esophagus - surgery; Female; Gastroenterology. Liver. Pancreas. Abdomen; Humans; Liver Cirrhosis - physiopathology; Liver Cirrhosis - surgery; Liver. Biliary tract. Portal circulation. Exocrine pancreas; Male; Medical sciences; Middle Aged; Other diseases. Semiology; Postoperative Period; Regional Blood Flow; Human; Stomach; Azygos vein; Liver; Pressure gradient; Ablation; Blood flow; Esophagus; Cirrhosis; Hepatic vein; Surgery; Blood vessel; Digestive diseases; Hemodynamics
• ISSN: 0017-5749; 1468-3288; 1458-3288
• DOI: 10.1136/gut.30.10.1396

Azygos venous blood flow and other haemodynamic parameters were measured in 14 cirrhotic patients to investigate the effects of a non-shunting operation, oesophageal transection with paraoesophagogastric devascularisation. Azygos venous blood flow measured by the local continuous thermal dilution method was significantly reduced by 13.8% after the operation (428 (41) v 369 (33) ml/min). Hepatic venous pressure gradient (HVPG) was also significantly decreased from 14.5 (0.8) to 12.8 (0.7) mmHg (-11.8%). Cardiac output and routine liver tests did not change remarkably postoperatively. In this haemodynamic study before and after non-shunting operation, moderate but significant decreases were seen in azygos venous blood flow and portal pressure (HVPG), without substantial changes in systemic circulation. This suggests that blood flow through the portosystemic collaterals other than oesophageal varices may be decreased but still adequate after the operation. Well preserved portosystemic collaterals without oesophageal varices are thus considered an optimally balanced state after non-shunting operation.