2019 American College of Rheumatology/European League Against Rheumatism classification criteria for IgG4-related disease by Wallace et al

[...]1 of 40 patients (2.5%) with definite IgG4-RD was not reclassified as having IgG4-RD according to the 2019 ACR/EULAR criteria. [...]patient 1 obtained only 4 points and could not be reclassified as having IgG4-RD despite the increased concentration of serum IgG4 (4 points). During this period,...

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Published inAnnals of the rheumatic diseases Vol. 81; no. 9; p. e179
Main Authors Yoo, Byung-Woo, Song, Jason Jungsik, Park, Yong-Beom, Lee, Sang-Won
Format Journal Article
LanguageEnglish
Published England BMJ Publishing Group Ltd and European League Against Rheumatism 01.09.2022
BMJ Publishing Group LTD
Subjects
autoantibodies
autoimmune diseases
autoimmunity
Biopsy
Classification
Correspondence
Glucocorticoids
Immunoglobulin G
Lymphatic system
Medical imaging
Mycophenolate mofetil
Mycophenolic acid
Patients
Rheumatism
Rheumatology
autoimmune diseases
autoimmunity
autoantibodies
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Summary:[...]1 of 40 patients (2.5%) with definite IgG4-RD was not reclassified as having IgG4-RD according to the 2019 ACR/EULAR criteria. [...]patient 1 obtained only 4 points and could not be reclassified as having IgG4-RD despite the increased concentration of serum IgG4 (4 points). During this period, the serum IgG4 concentration had consistently increased, and the last two biopsy samples showed markedly increased infiltrating IgG4+ cells counts. [...]this patient was diagnosed with IgG4-related lymphadenopathy3 4 and received glucocorticoids and mycophenolate mofetil.5 We believe that this paper will be of interest to the readership of the journal because of its immediate clinical impact to patients with suspected IgG4-related disease, as well as our recommendations to physicians attempting to diagnose them.
Bibliography:SourceType-Other Sources-1
content type line 63
ObjectType-Correspondence-1
ISSN:0003-4967
1468-2060
DOI:10.1136/annrheumdis-2020-217086