Chalcones and their potential role in inflammation
Chalcones are a group of phenolic compounds which possess a wide variety of cytoprotective and modulatory functions. They have been shown to possess antioxidant, oxygen scavenging and anti-inflammatory properties in a variety of experimental systems and can trigger the intracellular cascade of prote...
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Published in | Mini reviews in medicinal chemistry Vol. 8; no. 12; p. 1224 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Netherlands
01.10.2008
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Subjects | |
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Abstract | Chalcones are a group of phenolic compounds which possess a wide variety of cytoprotective and modulatory functions. They have been shown to possess antioxidant, oxygen scavenging and anti-inflammatory properties in a variety of experimental systems and can trigger the intracellular cascade of protective pathways offering a promising stratagem for therapeutic applications. In this research we will review the anti-inflammatory effect of chalcone derivatives and new approaches. |
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AbstractList | Chalcones are a group of phenolic compounds which possess a wide variety of cytoprotective and modulatory functions. They have been shown to possess antioxidant, oxygen scavenging and anti-inflammatory properties in a variety of experimental systems and can trigger the intracellular cascade of protective pathways offering a promising stratagem for therapeutic applications. In this research we will review the anti-inflammatory effect of chalcone derivatives and new approaches. |
Author | Kontogiorgis, C Mantzanidou, M Hadjipavlou-Litina, D |
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Snippet | Chalcones are a group of phenolic compounds which possess a wide variety of cytoprotective and modulatory functions. They have been shown to possess... |
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SubjectTerms | Animals Anti-Inflammatory Agents - pharmacology Antioxidants - metabolism Chalcones - pharmacology Chemistry, Pharmaceutical - methods Drug Design Free Radical Scavengers Humans Inflammation Leukotriene B4 - chemistry Models, Biological Models, Chemical Neutrophils - metabolism Oxygen - chemistry Phenol - chemistry |
Title | Chalcones and their potential role in inflammation |
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