Chalcones and their potential role in inflammation
Chalcones are a group of phenolic compounds which possess a wide variety of cytoprotective and modulatory functions. They have been shown to possess antioxidant, oxygen scavenging and anti-inflammatory properties in a variety of experimental systems and can trigger the intracellular cascade of prote...
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| Published in | Mini reviews in medicinal chemistry Vol. 8; no. 12; p. 1224 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
Netherlands
01.10.2008
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| Subjects | |
| Online Access | Get more information |
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| Abstract | Chalcones are a group of phenolic compounds which possess a wide variety of cytoprotective and modulatory functions. They have been shown to possess antioxidant, oxygen scavenging and anti-inflammatory properties in a variety of experimental systems and can trigger the intracellular cascade of protective pathways offering a promising stratagem for therapeutic applications. In this research we will review the anti-inflammatory effect of chalcone derivatives and new approaches. |
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| AbstractList | Chalcones are a group of phenolic compounds which possess a wide variety of cytoprotective and modulatory functions. They have been shown to possess antioxidant, oxygen scavenging and anti-inflammatory properties in a variety of experimental systems and can trigger the intracellular cascade of protective pathways offering a promising stratagem for therapeutic applications. In this research we will review the anti-inflammatory effect of chalcone derivatives and new approaches. |
| Author | Kontogiorgis, C Mantzanidou, M Hadjipavlou-Litina, D |
| Author_xml | – sequence: 1 givenname: C surname: Kontogiorgis fullname: Kontogiorgis, C organization: Department of Pharmaceutical Chemistry, School of Pharmacy, Aristotle University of Thessaloniki, Thessaloniki, Greece – sequence: 2 givenname: M surname: Mantzanidou fullname: Mantzanidou, M – sequence: 3 givenname: D surname: Hadjipavlou-Litina fullname: Hadjipavlou-Litina, D |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/18855737$$D View this record in MEDLINE/PubMed |
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| SubjectTerms | Animals Anti-Inflammatory Agents - pharmacology Antioxidants - metabolism Chalcones - pharmacology Chemistry, Pharmaceutical - methods Drug Design Free Radical Scavengers Humans Inflammation Leukotriene B4 - chemistry Models, Biological Models, Chemical Neutrophils - metabolism Oxygen - chemistry Phenol - chemistry |
| Title | Chalcones and their potential role in inflammation |
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