Chalcones and their potential role in inflammation

Chalcones are a group of phenolic compounds which possess a wide variety of cytoprotective and modulatory functions. They have been shown to possess antioxidant, oxygen scavenging and anti-inflammatory properties in a variety of experimental systems and can trigger the intracellular cascade of prote...

Full description

Saved in:
Bibliographic Details
Published inMini reviews in medicinal chemistry Vol. 8; no. 12; p. 1224
Main Authors Kontogiorgis, C, Mantzanidou, M, Hadjipavlou-Litina, D
Format Journal Article
LanguageEnglish
Published Netherlands 01.10.2008
Subjects
Animals
Anti-Inflammatory Agents - pharmacology
Antioxidants - metabolism
Chalcones - pharmacology
Chemistry, Pharmaceutical - methods
Drug Design
Free Radical Scavengers
Humans
Inflammation
Leukotriene B4 - chemistry
Models, Biological
Models, Chemical
Neutrophils - metabolism
Oxygen - chemistry
Phenol - chemistry
Online AccessGet more information

Cover

More Information
Summary:Chalcones are a group of phenolic compounds which possess a wide variety of cytoprotective and modulatory functions. They have been shown to possess antioxidant, oxygen scavenging and anti-inflammatory properties in a variety of experimental systems and can trigger the intracellular cascade of protective pathways offering a promising stratagem for therapeutic applications. In this research we will review the anti-inflammatory effect of chalcone derivatives and new approaches.
ISSN:1389-5575
DOI:10.2174/138955708786141034