Comparison of CT colonography, colonoscopy, sigmoidoscopy and faecal occult blood tests for the detection of advanced adenoma in an average risk population

• Published in: Gut Vol. 58; no. 2; pp. 241 - 248
• Main Authors: Graser, A, Stieber, P, Nagel, D, Schäfer, C, Horst, D, Becker, C R, Nikolaou, K, Lottes, A, Geisbüsch, S, Kramer, H, Wagner, A C, Diepolder, H, Schirra, J, Roth, H J, Seidel, D, Göke, B, Reiser, M F, Kolligs, F T
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group Ltd and British Society of Gastroenterology 01.02.2009; BMJ Publishing Group; BMJ Publishing Group LTD
• Subjects: Adenoma - diagnosis; Aged; Aged, 80 and over; Biological and medical sciences; Colon - pathology; Colonic Polyps - diagnosis; Colonography, Computed Tomographic - methods; Colonoscopy; Colonoscopy - methods; Colorectal cancer; Colorectal Neoplasms - diagnosis; Contrast agents; Digestive system; Digestive system. Abdomen; Drug dosages; Endoscopy; Feces - chemistry; Female; Gastroenterology. Liver. Pancreas. Abdomen; Hemoglobins - analysis; Humans; Imaging, Three-Dimensional; Investigative techniques, diagnostic techniques (general aspects); Male; Medical sciences; Medical screening; Middle Aged; Occult Blood; Patients; Polyethylene glycol; Polyps; Prospective Studies; Radiation; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Rectum - pathology; Sample Size; Scanners; Sensitivity and Specificity; Sigmoidoscopy - methods; Tumors; Germany; Virtual colonoscopy; Sigmoidoscopy; Colonoscopy; Risk factor; Gastroenterology; Benign neoplasm; Adenoma; Colon; Endoscopy; Feces; Comparative study; Blood

Background and aims:This prospective trial was designed to compare the performance characteristics of five different screening tests in parallel for the detection of advanced colonic neoplasia: CT colonography (CTC), colonoscopy (OC), flexible sigmoidoscopy (FS), faecal immunochemical stool testing...