Exploring the minimal important difference in the treatment of paediatric obsessive-compulsive disorder using selective serotonin reuptake inhibitors

• Published in: BMJ mental health Vol. 27; no. 1; p. e300999
• Main Authors: Cohen, Sem E, Denys, Damiaan A J P, Mattila, Taina Kristiina, Storosum, Bram W C, de Boer, Anthonius, Zantvoord, Jasper Brian
• Format: Journal Article
• Language: English
• Published: England BMJ Publishing Group Ltd, Royal College of Psychiatrists and British Psychological Society 19.06.2024; BMJ Publishing Group LTD; BMJ Publishing Group
• Subjects: Adolescent; Benchmarks; Child; child & adolescent psychiatry; Correspondence; data interpretation, statistical; Gender; Humans; Mental depression; Neuroses; Obsessive compulsive disorder; Obsessive-Compulsive Disorder - drug therapy; Patients; Pediatrics; Psychiatry; Selective Serotonin Reuptake Inhibitors - therapeutic use; Serotonin; Teenagers; data interpretation, statistical; child & adolescent psychiatry

Study selection and analysis We used individual participant data from short-term double-blind, randomised, placebo-controlled trials with selective serotonin reuptake inhibitors (SSRIs) that were submitted to the Dutch Medicines Evaluation Board (MEB). Table 1 Patient characteristics at baseline Pla...