Hepatitis C virus clearance and gender

Bakr et al (Gut 2006;55:1183-7) , in a large population-based cross-sectional survey on hepatitis C virus (HCV) infection in Egypt, found that HCV clearance rates (ie, positive HCV antibodies and negative HCV-RNA test results) were significantly higher in women (44%) compared with men (33.7%, adjust...

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Bibliographic Details
Published inGut Vol. 56; no. 6; p. 884
Main Authors Stroffolini, T, Rapicetta, M, Di Stefano, R
Format Journal Article
LanguageEnglish
Published England BMJ Publishing Group Ltd and British Society of Gastroenterology 01.06.2007
BMJ Publishing Group LTD
BMJ Group
Subjects
Bias
Female
Gender
Hepacivirus - isolation & purification
Hepatitis
Hepatitis C
Hepatitis C - virology
Hepatitis C virus
Humans
Hypotheses
Infections
Letters
Male
Mortality
Research Design
RNA, Viral - blood
Sex Factors
Studies
Egypt
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Summary:Bakr et al (Gut 2006;55:1183-7) , in a large population-based cross-sectional survey on hepatitis C virus (HCV) infection in Egypt, found that HCV clearance rates (ie, positive HCV antibodies and negative HCV-RNA test results) were significantly higher in women (44%) compared with men (33.7%, adjusted odds ratio (OR) 1.77). [...]we agree with Stroffolini et al that differential mortality between chronically infected females and males may lead to biases in estimating differences in clearance rates in cross-sectional surveys.
Bibliography:PMID:17519492
Correspondence to:
 Dr T Stroffolini
 Department of Gastroenterology, S Giacomo Hospital, Rome, Italy; tommaso.stroffolini@iss.it
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ISSN:0017-5749
1468-3288
DOI:10.1136/gut.2006.116632